There’s always debate about stem cells and regenerative medicine, right? There are very strong opinions in our field. Here is a list of 10 current, provocative questions. I have my own ideas about the answers to these. Weigh in with comments with your answers. I’m going to do a follow up post with some discussion of the […]
10 provocative stem cell questions: what are your answers? Read More »
Below are the 2016 stem cell predictions I made last year and their status now color-coded near year’s end. Green is right, orange is mixed bag, and red is flat out wrong. Overall, I did better than most past years with only having entirely blown it on four. Stay tuned later this week for my 2017 predictions,
Grading my stem cell predictions for 2016: how’d I do? Read More »
I received a score of great nominations for the Stem Cell Person of the Year 2016 Award and have briefly described the twenty nominees below. The point of the award is to honor the top positive stem cell leader who specifically thinks outside the box and takes risks. I’ve started an on-line vote where you can vote once per day for
20 Nominees for Stem Cell Person of the Year 2016 Award Read More »
By Gaetan Burgio CRISPR/Cas9 genome editing has dramatically changed our way to perform biological experiments. While highly efficient and easy to use, one limitation with CRISPR/Cas9 mediated genome editing technology is the occurrence of off-target effects and the restriction of the PAM recognition sequence. Many modifications from the original system have been proposed to improve
Gaetan Burgio New Data & Theory on NgAgo versus CRISPR Read More »
Has it really been 10 years since induced pluripotent stem cells (aka IPS cells or IPSC) came onto the scene in the stem cell field? Yes, it was a decade ago that now Nobel Laureate Shinya Yamanaka (山中伸弥) published that seminal Cell paper on reprogramming to make mouse IPS cells and then human IPS cells
Yamanaka’s baby turns 10: ten IPS cell hot button bullet points Read More »
Each December I make stem cell predictions for the coming year and I did that for 2016 where I made 20 predictions. At around mid year I do a checkup on how my predictions are doing halfway and that is the purpose of this post. Below are my predictions that I made in 2015 for stem
Stem cell checkup: how are my 2016 predictions doing half way? Read More »
Here are some headlines & articles worth a look and some thought on stem cell and biomedical science more generally. Gallup finds in a new poll that 60% of Americans surveyed find human embryonic stem celsl research “largely acceptable”. On the other hand human reproductive cloning is highly frowned upon, sandwiched in the “highly unacceptable
Weekend reads: ES cell research polls well, Gordie Howe, MS, IPS cells, and more Read More »
What will the new year have in store for stem cells? 2016 promises to have many striking stem cell developments. Below are my top 20 stem cell predictions for what is to come this year in no particular order. Share your stem cell tea leaves in the comments please. Another stem cell biotech acquisition by pharma
List of 20 stem cell predictions for 2016 Read More »
After a seemingly endless period of review, the FDA has approved the genetically modified (GM) AquaBounty salmon for sale and consumption. Update: You might find my interview with George Church on CRISPR and gene modification interesting. I don’t see any particular reason to think that this GM fish as a food would pose any significant
FDA approves 1st GM animal (fast-growing salmon) to eat Read More »
CRISPR-ful Noah’s Ark? Even as much of the discussion surrounding powerful new gene editing and cloning technologies has centered on their possible use in humans, the creation of genetically modified (GM) and cloned animals has advanced at warp speed. Some of these efforts have been for research, which is justified. But many seem profit-centered and
Noah’s GMO ark: is it ethical to create GM or cloned animals for sale as pets? Read More »