Search Results for: 3-Person IVF

Steven Pinker interview: case against bioethocrats & CRISPR germline ban

Steven-Pinker

CRISPR-Cas9 gene editing technology is red-hot right now and I’ve been doing interviews with various thought leaders on it, which today includes Steven Pinker. This technology has great power for research in the lab and there are hypothetical transformative clinical applications of CRISPR too. The latter efforts could include experimental attempts at reversal of disease-causing …

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4 areas of debate on 1st human embryo genetic modification paper

human-genetic-modification

Last week was a big one for the life sciences in that we saw the milestone of the first ever published paper reporting human embryo genetic modification (see here and here). It was one of those situations where we knew it was coming, but it was still a jolt. Not surprisingly this event sparked intense discussion …

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Juan Carlos Izpisua Belmonte Cell Paper on Gene Editing for Mitochondrial Disease

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The Juan Carlos Izpisua Belmonte group published a Cell paper today on using gene editing to reverse mutations associated with human mitochondrial disease. The paper is Reddy, et al. and is entitled, “Selective Elimination of Mitochondrial Mutations in the Germline by Genome Editing”. The authors report success using TALEN-based gene editing or mitochondrial-direct restriction enzyme (mito-ApaLI) …

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ISSCR calls for moratorium on clinical application of human germline nuclear genome editing

ISSCR_logo

The International Society for Stem Cell Research (ISSCR) just now released a new policy statement on human germline gene editing. The statement calls for a ban on clinical application of human germline gene editing technology. Here is the brief summary statement at the beginning: The International Society for Stem Cell Research calls for a moratorium on …

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Readers across the globe favor moratorium on gene editing of human germ cells in poll

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In a still ongoing on-line poll, readers of this blog show a pattern of consistently favoring a moratorium on genetic modification of human germ cells. With more than 150 votes cast, the top two answers are ‘strongly favor’ and ‘favor’ a moratorium on human germline genetic modification. Only 15% strongly opposed a moratorium. Overall those …

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George Church on Germline Human Genetic Modification

George-Church

I recently interviewed leading genomics scientist George Church on the ways that trends in genomics are changing our world and the possibility of heritable human genetic modification. His answers suggest that genomics and gene editing are poised to radically change our world and to literally change us. Here’s the George Church interview you’ve all been waiting …

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The Odd Couple of Cloning Research: Mitalipov & Woo Suk Hwang Unite

Hwang-Mitalipov

Remember that old TV show the Odd Couple with very proper Felix Unger and his polar opposite Oscar Madison who has all kinds of baggage? They’ve cloned it into a remake to be on TV soon here in the US in 2015. It seems only fitting then that actual human cloning research has a new …

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Human GMO Method Given OK by UK Parliament in Historic Vote

human-GMO

The UK Parliament just voted to legalize the production of genetically modified human beings. To my knowledge, this is the first time in history that such a vote has given the green light to make GMO human beings in any country of the world. There are other hurdles before this method can actually be used including the …

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When the state & ‘rogue’ scientists collide: case of China & CRISPR baby guy He Jiankui (贺建奎)

He-Jiankui-贺建奎

What happens next to He Jiankui (贺建奎) or as some people now refer to him, the “CRISPR baby guy”? China has a challenging situation to resolve here, but such conflicts between scientists and governments have happened regularly in history. When scientists go “rogue” (i.e. don’t conform to norms or ethical standards in an extreme way or …

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UK Biologist Niakan Asks to Make GM Human Embryos For Research

Kathy-Niakan

UK biologist Kathy Niakan has asked governmental permission to make GM human embryos using CRISPR. Earlier this year, a research team in China crossed a scientific line for the first time in history by using gene editing technology called CRISPR-Cas9 to make genetically modified (GM) human embryos. Other researchers around the world including now one …

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