A new paper focused on human and other chimeras just came out today in Cell reporting a number of findings, but most strikingly successful generation of human-pig chimeras in utero. The paper, entitled, “Interspecies Chimerism with Mammalian Pluripotent Stem Cells” describes various chimeras including mouse-rat ones, although those have previously been reported. This work comes […]
Perspectives on pig human chimera paper Read More »
Here is a hub for 2017 stem cell and regenerative medicine meetings. If you do not see your meeting, please let me know and I will include it. Change– I’m also going to be listing online courses (in red) this year. This list is meant to be as inclusive as possible, but by listing specific
Stem Cell Meetings & Conferences 2017 Read More »
By Gaetan Burgio CRISPR/Cas9 genome editing has dramatically changed our way to perform biological experiments. While highly efficient and easy to use, one limitation with CRISPR/Cas9 mediated genome editing technology is the occurrence of off-target effects and the restriction of the PAM recognition sequence. Many modifications from the original system have been proposed to improve
Gaetan Burgio New Data & Theory on NgAgo versus CRISPR Read More »
It’s been a busy few weeks for the CRISPR arena so I’ve made a CRISPR Update. I’ve listed below links to some commentaries and key developments. Fun Video interview on Read Science! with Joanne Manaster on my new book on CRISPR in humans, GMO Sapiens. CRISPR: Pursuit of profit poisons collaboration, Nature piece by Jacob Sherkow
CRISPR Update: Patents, Embryos, & IPOs, oh my Read More »
A new paper was recently published on CRISPR of human embryos for genetic modification. I’ve got to read this publication more carefully, but here’s a quick initial take on this human CRISPR 2.0 study. The paper is Kang, et al. and is entitled “Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing”.
New Paper on CRISPR of Human Embryos Highlights Serious Tech Problems Read More »
With the approval today of the use of CRISPR in human embryos, the UK continues its recent trend toward a more permissive regulatory policy on human genetic modification. There are both risks and scientific benefits that come along with this trend. Last year the UK approved an experimental technology with the goal of preventing the
CRISPR embryo OK signals ongoing liberal UK trend on human modification Read More »
I’ll be on Talking Biopolitics live tomorrow to discuss my new book, GMO Sapiens. You can RSVP at that link. You can get the Kindle version of the book here or the soft or cover versions at the publisher site here. Nathaniel Comfort will be interviewing me on the book and we’ll also be taking
Join discussion of my new book GMO Sapiens on Talking Biopolitics tomorrow Read More »
The patent dispute on CRISPR between UC/Jennifer Doudna and The Broad/Feng Zhang has been the subject of major attention including in a recent piece on Stanford Center for Law & Biosciences Blog. There is a lot of confusion over this important CRISPR dispute so I turned to a patent expert for their take on this via an interview
Patent expert weighs in on CRISPR dispute between UC & Broad Read More »
I try to catch up on my science reading over the weekends and evenings. Here’s my recommended weekend reading on stem cells & science. Did I miss anything especially cool? Let me know in the comments. Direct reprogramming of skin cells into insulin-producing cells. I love direct reprogramming. Healios and Athersys Enter Into Regenerative Medicine Partnership.
Recommended weekend reading on stem cells & science Read More »
CRISPR is the hottest new biotechnology and the top development of 2015 according to Science Magazine. What will the new year of 2016 bring on the CRISPR front? It’s clear there will be more meetings on CRISPR ethics and policy (heck, we are having one right here at UC Davis on May 26), but what
CRISPR predictions for New Year of 2016 Read More »