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Interview with Jane Lebkowski on Asterias FDA-approved Stem Cell Trial

August 28, 2014 / Professor Paul Knoepfler, Ph.D. / 1 Comment

The BioTime subsidiary, Asterias, has received FDA approval for a combined Phase I/IIa clinical trial of OPC1 for treating spinal cord injury. BioTime (BTX) and Asterias (ASTY) have picked up the portfolio of the former Geron clinical trial using oligodendrocyte precursor cells (OPC). Asterias also acquired a second element from Geron in the form of a lung […]

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Interview with Ted Harada Part 2: Right To Try, Neuralstem, and How He’s Doing

August 24, 2014 / Professor Paul Knoepfler, Ph.D.

This is Part 2 of my interview with ALS and stem cell advocate, Ted Harada. You can read Part 1 of my talk with Ted on where things stand today with ALS, the FDA, and the Ice Bucket Challenge. What’s your opinion of the “Right To Try” law in Colorado and the concept more generally?

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Key questions for stem cell field bouncing around on a Friday morning

August 22, 2014 / Professor Paul Knoepfler, Ph.D. / 7 Comments

What are the most interesting questions for the stem cell field in 2014 right now? What’s on your mind? I’m not going to give this deep thought, but rather just list those questions bouncing around at the moment in no particular order. You can see a lot of translational/clinical things are on my mind. I’ve

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Ted Harada Interview Part 1: Stem Cells for ALS, More

August 21, 2014 / Professor Paul Knoepfler, Ph.D.

Ted Harada is a wonderful patient advocate for the stem cell field and for the development of safe and effective stem cell products to treat ALS. Ted has ALS and received stem cell-based treatments for it with surprising, very encouraging results. The Harada family is pictured at left with Ted, his wife Michelle as well as

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Great News: FDA Nod For ViaCyte IND of Diabetes Stem Cell-Based Product

August 20, 2014 / Professor Paul Knoepfler, Ph.D. / 8 Comments

Type 1 Diabetes is a huge global problem. Where are the solutions that would compliment or replace insulin therapy for diabetics? There haven’t been too many that have gotten very far, which makes the news of a potential stem cell-based therapy moving along in the pipeline all the more exciting. ViaCyte (see more posts here,

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You’ve got to see these fun stem cell videos including contest winner

August 18, 2014 / Professor Paul Knoepfler, Ph.D. / 3 Comments

For the last month I’ve been accepting entries to my blog’s stem cell videos contest. This video contest follows up on other fund and educational contests I’ve run with prizes including a stem cell essay contest. In addition I do an annual Stem Cell Person of the Year Award with a $1,000 prize, which I personally pay

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Stem Cell Person of the Year 2014 Award: Your Top Candidate?

August 17, 2014 / Professor Paul Knoepfler, Ph.D. / 4 Comments

Who should win the 2014 Stem Cell Person of the Year Award? Who has been the single most important, influential person in the world of stem cells this year? Who has made the biggest positive contribution in 2014? On Monday, October 1, I will start taking formal nominations for the Stem Cell Person of the

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Challenge tries to cancel Yamanaka iPS cell patent

August 14, 2014 / Professor Paul Knoepfler, Ph.D. / 66 Comments

A new patent dispute has exploded in the stem cell field related to induced pluripotent stem (iPS) cells. What’s going on? In 2006, Shinya Yamanaka reported cellular reprogramming to create mouse induced pluripotent stem (iPS) cells in Cell and the next year multiple groups along with Yamanaka’s reported creating human iPS cells. It’s no exaggeration

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Stem Cell Community Tribute to Yoshiki Sasai (笹井芳樹)

August 12, 2014 / Professor Paul Knoepfler, Ph.D. / 61 Comments

This post is a tribute to the late Dr. Yoshiki Sasai (笹井芳樹). If you would like your name added to this tribute please let me know. You are also welcome to add your own tributes in the comments. In an era when the emerging field of regenerative medicine is just beginning to take wing, we

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Where will STAP cell mess go from here & key unanswered questions

August 10, 2014 / Professor Paul Knoepfler, Ph.D. / 3 Comments

In some ways it’s hard to imagine that it was only just over 6 months ago that Nature published the two STAP cell papers by a collaborative team of Japanese and American researchers. It feels like years have gone by since then because so much has happened related to the STAP mess including the retraction of the

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