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‘I’d need a drink’: WaPo deep dive on clinic firm Lung Health Institute

December 7, 2019 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Washington Post reporters William Wan and Laurie McGinley have a new piece on the unproven regenerative clinic firm the Lung Health Institute. This article has a number of surprises and new insights. Previously the Lung Health Institute was called just the Lung Institute. It was recently acquired by the publicly-traded company H-CYTE, stock symbol HCYT. In the […]

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Unnatural Selection review: captivating mind-bender but needed more science

October 28, 2019 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Unnatural-Selection-with-patient-Jackson-Kennedy

Today’s post is a review of Unnatural Selection, the new Netflix science docuseries focused on CRISPR and other disruptive genetic and reproductive technologies. The show is an interesting mix of personalities and stories from patients, scientists, biohackers, and more. One patient thread is the story of a wonderful little boy named Jackson Kennedy. He wants

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ViaCyte Q&A: CRISPR Tx quick progress, ongoing diabetes trial, & more

September 25, 2019 / Professor Paul Knoepfler, Ph.D. / 9 Comments

ViaCyte is one of the most exciting stem cell and regenerative medicine biotech companies so I like to try to check in with them regularly. Today’s post is my new interview with ViaCyte leader Paul Laikind on recent developments. We had a great chat about the science and how things are looking upbeat for the

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FDA Regenerative Medicine Advanced Therapy RMAT designations jump to 36

September 24, 2019 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Peter-Marks-Regenerative-Medicine-Advanced-Therapy-Designation-RMAT-

This post includes my updated list of firms/products that have received FDA regenerative medicine advanced therapy designation or RMAT, which are in the public domain. The numbers really jumped in the last month. I’m assuming for the purposes of this resource page that all self-reports are accurate. Note that the links embedded into the firm

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Richard Garr Q&A on his new Right-To-Try firm Beacon of Hope

September 12, 2019 / Professor Paul Knoepfler, Ph.D. / 6 Comments

A new right-to-try company called Beacon of Hope is stirring some intense discussion. State and federal right-to-try laws could potentially change the fabric of how many investigational studies are conducted. That may happen through firms like Beacon of Hope. However, we don’t know much about the firm. I’m hoping to help change that. Today’s post

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Northwestern abruptly ending Burt HSCT autoimmune trials

August 29, 2019 / Professor Paul Knoepfler, Ph.D. / 55 Comments

“HSCT Chicago Clinic Closing!” is the startling header in all caps on a patient-run Facebook page about a stem cell therapy clinical trial program at Northwestern University. What’s going on? Unfortunately, the promising field of hematopoietic stem cell transplantation (HSCT) for multiple sclerosis (MS) and other autoimmune diseases seems to have suffered an unexpected setback

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Dragon book

July 26, 2019 / Professor Paul Knoepfler, Ph.D.

My daughter Julie and I have written a book together entitled, “How to Build a Dragon or Die Trying, A satirical look at cutting edge science.” The book will be out sometime in June most likely. This is a very different kind of book than my first two, Stem Cells: An Insider’s Guide and GMO

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Good news science digest: HIV, brain, CRISPR, cats vs. dogs, space, & more

July 25, 2019 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Every now and then I collect a bunch of recent science good news that I’ve come across. Here are some past ‘good news’ posts. Today’s post includes such a recent collection and some funny stuff too at the end. Enjoy! BTW, science is not necessarily all about stem cells, right? Talk about good news. 1,000th

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How to Build a Dragon or Die Trying: check out new book with my daughter Julie

April 22, 2019 / Professor Paul Knoepfler, Ph.D.

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Sexual Medicine Society on Unproven Regenerative Therapies for Erectile Dysfunction

April 10, 2019 / Professor Paul Knoepfler, Ph.D. / 3 Comments

Sexual-Medicine-Society-of-North-America

There are many potential causes of erectile dysfunction or ED and a host of ideas about how to treat it. Some approaches to erectile dysfunction are evidence-based and even have been rigorously proven such as the drugs Viagra and Cialis, which increase blood flow to the penis. Depending on the causes of the dysfunction, these

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