What’s your lab like? What do you work on? What are you most excited about? Is your lab hiring? What are your lab traditions? Superstitions? How messy/clean is your lab? You can see a picture of me in my lab below about 5-6 years ago…the usual busy semi-clutter of a lab. You can win $100 […]
Lab tour video contest: $100 prize Read More »
So everyone is buzzing about the CRISPR patent court decision (which BTW I think was flawed but that’s for another post), but the research roars on at warp speed. Here are 7 recent CRISPR articles that caught my attention. What are your favorite recent CRISPR papers? Genome surgery using Cas9 ribonucleoproteins for the treatment of
7 cool recent CRISPR articles Read More »
It was just over a decade ago that I started making websites and it’s been a wild ride. My first site was at the domain name www.chromatin.com, which I was fortunate to have been able to get for a good deal way back when…I think in 2005. You can see here an early 2007 copy
~10th anniversary of my 1st website: reflecting on wild ride Read More »
A new paper focused on human and other chimeras just came out today in Cell reporting a number of findings, but most strikingly successful generation of human-pig chimeras in utero. The paper, entitled, “Interspecies Chimerism with Mammalian Pluripotent Stem Cells” describes various chimeras including mouse-rat ones, although those have previously been reported. This work comes
Perspectives on pig human chimera paper Read More »
The 21st Century Cures Act specifies some new FDA rules about investigational stem cell-based regenerative medicine therapies and perhaps most importantly defined a new class of product called a “Regenerative Advanced Therapy” or RAT, which is entitled to an expedited review. The FDA already has a new page up on RATs, which specifies the specifics of
FDA Regenerative Advanced Therapy Designation Rules Are Up in Response to Cures Act Read More »
A new Cell paper from Juan Carlos Izpisua Berlmonte’s group has made headlines about anti-aging across the globe because it suggests that the four core induced pluripotent stem cell (IPSC) factors use by Shinya Yamanaka to make IPSC can reverse aging. I’ve pasted the graphical abstract from the paper below and done a quick journal club style
Quick journal club on IPSC anti-aging paper: cool, but outstanding questions Read More »
One of the hottest topics in the world of stem cells this year has been the REGROW ACT and at a larger level the movement for changes in FDA oversight of investigational regenerative medicine therapies (see my past posts on it here), so the related provisions in the 21st Century Cures Act are stirring much
Chat with Michael Werner of ARM on Cures Act regenerative medicine provisions Read More »
I’m organizing my own thinking on how Trump’s election will impact science and stem cell/regenerative medicine research in particular and will post on that soon, but for now here are some of the early responses I’ve seen where scientists comment on this big, unexpected event and key questions. These are in addition to the almost
A collection of scientist responses to Trump election Read More »
One of the biggest stem cell news stories of 2016 has been the REGROW Act, a bill intended to accelerate investigational stem cell and regenerative medicine therapies to patients by lessening FDA oversight, but in the last couple months REGROW has mostly disappeared from the news. Will REGROW do a reappearing act like some kind
REGROW Act to do reappearing act? Read More »
Editor’s note: this is a guest post from Dr. Semenow on her new educational DNA game that also invokes stem cells. She has the remarkable distinction of having been the first woman who was a science Ph.D. student at Caltech. Stay tuned for my coming interview with her on her experiences in science. Her Kickstarter campaign
DNA Ahead Game & More Struts Its Stuff Read More »