Advanced Cell Technology (ACT) has confirmed that one of the patient in a clinical trial that it is running for treatment of macular degeneration, the leading cause of blindness worldwide, has shown a striking improvement in vision. The patient reportedly had 20/400 vision prior to treatment and now has 20/40 vision after treatment. ACT uses an […]
Striking improvement in vision in one ACT trial participant Read More »
Yesterday’s report of human therapeutic cloning to make embryonic stem (ES) cell lines is a big deal. I support the work and I believe it is very important. People’s reactions to it vary wildly depending on their agendas of course. This post is a no-nonsense overview of the main points. My overall point. This is
5 human therapeutic cloning talking points dissected Read More »
UPDATE: Unfortunately the Betatrophin paper discussed here originally back in 2013 has now largely been proven to have come to incorrect conclusions (for more read this). Today Harvard Stem Cell Institute (HSCI) reported the discovery, in a paper in Cell by Harvard Professor Doug Melton, of a powerful new hormone called Betatrophin that can stimulate
Doug Melton Betatrophin Discovery Points to Future Diabetes Treatment? Read More »
Harvard Stem Cell Institute (HSCI) is making a big announcement today about stems, the biggest they say in their almost decade-long existence. Last night I speculated/predicted some possible announcements. Today I’m betting they will announce the discovery of a novel factor called Betatrophin. More on Betatrophin in a minute, but first why do I think
What is Betatrophin & why is Harvard so excited about it? Read More »
Back-to-back papers (here and here) in Nature Biotechnology report the transdifferentiation (now often simply referred to as “direct reprogramming”) of plain old fibroblasts into brain cells called oligodendrocyte progenitor cells (OPCs). OPCs are a remarkably useful kind of brain cell that generates myelin, which insulates nerves. OPCs are thought to have great therapeutic potential for
Τι είναι τα βλαστοκύτταρα; Greek. Τι είναι τα βλαστοκύτταρα; Το ανθρώπινο σώμα περιέχει εκατοντάδες διαφορετικά είδη κυττάρων που είναι απαραίτητα για την καθημερινή μας υγεία. Τα κύτταρα αυτά είναι υπεύθυνα για διάφορες βασικές λειτουργίες, όπως το να κάνουν την καρδιά μας να χτυπά, τον εγκέφαλό μας να σκέφτεται, τα νεφρά μας να καθαρίζουν το αίμα,
Τι είναι τα βλαστοκύτταρα Read More »
Was sind Stammzellen? Der menschliche Körper enthält Hunderte von verschiedenen Zellarten, die für unsere tägliche Gesundheit wichtig sind. Diese Zellen sind verantwortlich für das tägliche Funktionieren unseres Körpers, wie das Schlagen des Herzes, das Denken des Gehirns, das Säubern unseres Blut durch die Nieren, das Ersetzen unsere Hautzellen, und so weiter. Die wichtige und einzigartige
Was sind Stammzellen? Read More »
Davis, CA and UC Davis are very unique. We were driving down to a favorite hiking spot, Putah Creek this past weekend, and noticed a sign along the way. It dawned on me just wildly unusual this sign we always drive by really is if you think about it (see at right). I think Davis,
Get your germplasm! Read More »
Today is part of 4 (the last) of my interview with Dr. Arnold Caplan, MSC godfather and guru. You can read parts 1-3 of the interview here, here, and here. In this post I focus on my discussion with Caplan on translation of stem cells to patients and the FDA. During our conversation we talked about some
Interview with Arnold Caplan, Part 4: the FDA and the Future Read More »
CIRM recently held an “elevator pitch” (also sometimes known as an “elevator speech”) contest amongst its grantees. The San Francisco Chronicle even covered this contest (and also here). Kevin McCormack, Sr. Director of Public Communications and Patient Advocate Outreach at CIRM, described the contest in, appropriately enough, a speech. As best as I can tell 56 scientists participated. By way
My top 3 favorite CIRM elevator pitches Read More »