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New England Journal of Med: most Americans support ES cell research

November 17, 2011 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Today, an authoritative article was published in the prestigious New England Journal of Medicine (NEJM) that included some of the most comprehensive polling of attitudes in the U.S. and around the world on embryonic stem cell (ESC) or ES cell research. Their findings indicate very widespread and deep support for ESC research around the globe including in […]

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Perspectives on Geron ending stem cell program

November 16, 2011 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Many of us have been discouraged by Geron decision to end their stem cell program, which included products based on human embryonic stem (ES) cells, but let’s keep some perspective on this and not give up hope. The opponents of hope want us to give up. They who have waged their own self-proclaimed war on

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The day after Geron news: a realistic outlook for the stem cell field

November 15, 2011 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Yesterday Geron announced it would be immediately stopping its stem cell research program. What does this mean? While this program has (or should I say “had”) a number of elements, at its heart was of course its hESC-based OPC drug (GRNOPC1) for spinal cord injury, which was in an FDA-approved Phase I Clinical Trial that

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Bad news as Geron to quit hESC SCI trial for financial reasons

November 14, 2011 / Professor Paul Knoepfler, Ph.D. / 6 Comments

Reportedly, Geron has decided to only focus on cancer research and for financial reasons has shut down its hESC trial for spinal cord injury. This is a very sad day for stem cell science. (Update in 2020: the firm still exists, but is working in different areas. The stock has struggled.) No more spinal cord

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More on Myc: meet the “Miz’s” in our new paper

November 13, 2011 / Professor Paul Knoepfler, Ph.D. / 1 Comment

I recently did a post telling you about one of my favorite molecules, Myc, which is important not only in cancer but also in most, if not all stem cells including iPS cells. There’s a lot more to Myc and how it does it’s tricks in embryonic stem cells and iPS cells. It cannot do

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Key points about adult versus embryonic stem cells

November 8, 2011 / Professor Paul Knoepfler, Ph.D.

What with the Mississippi “personhood” amendment up for a vote today and also the Vatican Adult Stem Cell Conference beginning tomorrow, I thought today was a good time for a post about adult versus embryonic stem cells. Does stem cell research have to be either/or? Adult or stem? Can’t someone be for both adult and

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Want to understand stem cells? Then you have to know Myc

November 6, 2011 / Professor Paul Knoepfler, Ph.D. / 1 Comment

What is Myc? Often when we dig a little into the science of stem cells, people get turned off by all the strange names of molecules and jargon. However, whether you are a scientist, patient, investor, reporter, etc. there are some aspects of stem cell science that are ‘musts’ to know about. For example, you

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Check out new blog about stem cells by Keri Kimler

November 1, 2011 / Professor Paul Knoepfler, Ph.D. / 1 Comment

I highly recommend that you guys check out the new blog by my friend, Keri Kimler. Keri is an awesome resource about stem cell research and her blog is not surprisingly, a wonderful source of information too. You can see Keri in this video from the World Stem Cell Summit: Keri is Vice Chair of

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Six fun, amazing, sometimes secret things to do in Seattle

October 28, 2011 / Professor Paul Knoepfler, Ph.D. / 4 Comments

Every now and then I do a post on something fun and non-science related, and today it’s all about Seattle. Since it’s Friday, don’t you wish you were on vacation in Seattle? If you can ever imagine visiting Seattle in the near future, bookmark this page because I give suggestions for great things (some that

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You know about spam, but what does ham have to do with blogging?

October 26, 2011 / Professor Paul Knoepfler, Ph.D. / 1 Comment

I love readers’ comments on my blog, but in addition to those I get a huge number of spam comments. I wish there were a lot more comments so I hope that that builds over time. One challenge to having a dialogue via comments on a blog is that there is so much spam. How

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