Search Results for: book

Highlights FOGM18 Day 1: Data from Ancient Dirt, Genomics Dilemmas, CAR-T, CRISPR

/ / 2 Comments
FOGM-venue-Scripps-Seaside-Forum

There are many genomics meetings out there these days, but The Future of Genomic Medicine meeting (#FOGM18) at Scripps in La Jolla is one of my favorites. This meeting is uniquely empowering. The people and the talks combine for a one-of-a-kind experience. The venue doesn’t hurt either at the Scripps Seaside Forum. The evening before the meeting […]

Highlights FOGM18 Day 1: Data from Ancient Dirt, Genomics Dilemmas, CAR-T, CRISPR Read More »

Is monkey cloning a breakthrough or a bad idea?

/ / 10 Comments
Monkey-clones

Is monkey cloning a good idea? We’re about to find out. A new Cell paper today reports the first cloning of monkeys via somatic cell nuclear transfer (SCNT), raising many questions. The paper from a team led by Qiang Sun is entitled, “Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer.” The highlight bullet points

Is monkey cloning a breakthrough or a bad idea? Read More »

Hope & hype on unpublished Huntington’s Disease trial splashy news

/ / 3 Comments
Huntingtons-brain-MRI

Some conditions like Huntington’s Disease are so bad and there are no treatments such that any bit of encouraging news can be cause for legitimate excitement, but at the same time things can go too far potentially, especially if there is news coverage not backed up by a published paper or some other definitive source

Hope & hype on unpublished Huntington’s Disease trial splashy news Read More »

7 tech hurdles to human germline CRISPR

/
Human-crispr-challenges

Human germline CRISPR raises major bioethical considerations, but what about technical issues? Setting aside the many ethical issue about the general idea of human modification itself, could this really work? Yes in theory it could, but there are some very tough technological challenges that could and likely would cause failures or unacceptable outcomes at many steps

7 tech hurdles to human germline CRISPR Read More »

Countering that Pro-Heritable Human CRISPR WSJ Piece

/ / 9 Comments
human-embryo-modification

It’s germline, heritable human CRISPR time, right? Wrong. But the particularly enthusiastic supporters of heritable human CRISPR often cite hypothetical benefits in glowing terms, but either don’t mention risks or strongly downplay them. These fans also tend to leave alternative, proven and safe technologies such as preimplantation genetic diagnosis (PGD) out of the discussion or

Countering that Pro-Heritable Human CRISPR WSJ Piece Read More »

4 key reasons Mitalipov paper doesn’t herald safe CRISPR human genetic modification

/ / 2 Comments
CRISPR-dart-board

We can be confident that human genetic modification via CRISPR’ing of embryos soon will be safe and effective after that new exciting Mitalipov team paper, right? Wrong. The reality is far more complicated and interesting on the tech side. In a nutshell, I see the paper as a significant scientific, but not necessarily medical advance.

4 key reasons Mitalipov paper doesn’t herald safe CRISPR human genetic modification Read More »

CRISPR, human genetic modification, & a needed course correction

/ / 9 Comments
coverGMO-e1498086048321

Are designer babies made using CRISPR or other genetic modification technologies closer to reality today? If so, what exactly should we do about it? Researchers can use CRISPR to genetically modify just about any organism or its cells, but targeting humans is the subject of the most intense discussion including using CRISPR in the human germline

CRISPR, human genetic modification, & a needed course correction Read More »

Highlights of ISSCR2017 – A Biomedical Engineer’s Perspective

/
Agnes-Soos

ISSCR meeting review By Agnes Soos Amid the hustle and bustle of downtown Boston, nearly four thousand researchers and exhibitors gathered for the 15th Annual ISSCR Meeting. With presentations from over thirty plenary lectures, and dozens of others featured in concurrent sessions and the daily Innovation Showcases, there definitely was no shortage of exciting research

Highlights of ISSCR2017 – A Biomedical Engineer’s Perspective Read More »