Search Results for: cancer stem cells

For IPS cell mutations, some reassuring new data but validation still key

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Figure-1b

Over the years some scientists including yours truly have expressed concerns about the possibility that mutations could crop up during the reprogramming process to make induced pluripotent stem cells (IPS cells or IPSC). How concerned should we be about IPS cell mutations? A cool new paper, Bhutani, et al, in Nature Communications from a team led by […]

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Perspectives: no human genetic modification moratorium from organizers of #GeneEditSummit

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GeneEditSummit

I just got back from a historic summit on human genetic modification in Washington, D.C. New genetic modification technology, termed CRISPR-Cas9, has both made genetic modification a relatively simple matter for scientists and human genetic modification much more likely in the near future. Heritable human genetic modification could prevent some rare genetic diseases so there

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Live Blogging #GeneEditSummit Day 1 Post #3: human germline modification

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Robin-Lovell-Badge-Peter-Braude-George-Church

The post-lunch session is “Applications of Gene Editing Technology: Human Germline Modification”. Prior to hearing it I’m curious how cautious or gung-ho the speakers will be, or if their gestalt will be one of balance in the middle somewhere. Robin Lovell-Badge, The Francis Crick Institute, was the moderator of this session. He said, “We’d be

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Live Blogging #GeneEditSummit Day 1 Post #2: State of the Science, #CRISPR

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Human-gene-editing-science-session-small

Now we hear from the scientists on the front lines of CRISPR, covered in this post #2 of the Human Gene Editing Meeting. You can read Post #1 here. Jennifer Doudna starts off the big human gene editing science session on the current state of the human gene editing science and CRISPR. She gave an

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Weekend science reading: fantastic found links including on CIRM

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glioblastomaWiki

David Jensen reports on the future of CIRM as a “beautiful machine”. CIRM funds brain cancer research in a big way: Funding a clinical trial for deadly cancer is a no brainer. Glioblastoma is a fatal tumor that needs new clinical approaches so this is exciting. One of the goals of my lab is to find new

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Steven Pinker interview: case against bioethocrats & CRISPR germline ban

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Steven-Pinker

CRISPR-Cas9 gene editing technology is red-hot right now and I’ve been doing interviews with various thought leaders on it, which today includes Steven Pinker. This technology has great power for research in the lab and there are hypothetical transformative clinical applications of CRISPR too. The latter efforts could include experimental attempts at reversal of disease-causing

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