Podcast for Week of July 5 Topics –Stem Cell Tourism in the U.S. –CIRM –Article in the Hill by stem cell opponent –Stem cell hype on aging Podcast for Week of July 11 Topics: –two papers on stem cell-based tissue engineering and one on stem cell treatments for heart disease, –the Republican candidates for …
Yamanaka may have found a way to give exogenous Myc the boot from the iPS cell universe. It has always been a frustration in the iPS cell field that Myc, a proto-oncogene, is so important for reprogramming. Yes, you can make iPS cells (especially mouse) without Myc, but it can be orders of magnitude harder, …
Note that this post ¿Qué son las células madre? is one of our “Stem Cells Not Lost in Translation” series. You can see the full 2020 series of our stem cell white paper in 34 languages here. ¿Qué son las células madre? El cuerpo humano contiene cientos de diferentes tipos de células que son importantes …
What is a survivor? Dan Zenka, Senior VP of the Prostate Cancer Foundation, recently pondered this question in an excellent post on his blog. The post has also drawn more than 50 comments, which I found very interesting based on the range of opinions and different perspectives. The comments are about prostate cancer, but could …
Sheng Ding’s lab reports today in Cell Stem Cell (you can read it here) that they have replaced all genetic factors in a new iPS cell reprogramming method except Oct4. The other factors were replaced by chemical compounds. Thus, we continue a major transition in the iPS cell field away from genes and toward chemicals. …
From genes to chemicals: iPS cell field, reprogramming in transition Read More »
A paper just came out in PNAS entitled “Promotion of direct reprogramming by transformation-deficient Myc“. The main thrust of this paper is that the tumorigenic and pluripotency-related functions of Myc could be separated. It focused primarily on the lesser studied LMyc. The topic of the intertwined good (pluripotency) and bad (tumorigenicity) functions of Myc, addressed …
Tumorigenicity and Pluripotency teased apart? Not yet for Myc Read More »