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Advanced Cell Technology pub: Trial for Macular Degeneration

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The stem cell biotech Advanced Cell Technology (ACT) reported new, positive data in a paper in Lancet from their clinical trials using retinal pigmented epithelial cells (RPEs) made from human embryonic stem cells (hESC) for treatment of different forms of macular degeneration (MD). The paper was entitled “Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related […]

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BioTime Cell Cure Files IND with FDA for ES cell AMD therapy

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Cell-Cure-Logo

Stem cell biotech BioTime announced the news today that its subsidiary Cell Cure Neurosciences (Cell Cure) has filed an IND with the FDA for an embryonic stem (ES) cell-based therapy for Dry age-related macular degeneration (AMD). The product to be tested is OpRegen, which the company indicates is “the first IND for an ES cell-based

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Interview with Clinicaltrials.gov Director Deborah Zarin

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This post is the first in a series about the Clinicaltrials.gov website. This piece is an interview the Director, Dr. Deborah Zarin. I want to thank her for taking the time to answer my questions. Later, I will post Part 2 in which I discuss my concerns about the trend of for-profit stem cell clinic trials

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Holding Institutions Responsible for Research Misconduct: the recent case of a death of stem cell scientist

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Guest post on Research Misconduct. By Zubin Master Scientist Yoshiki Sasai, age 52, committed suicide and was found dead on August 5, 2014. Sasai was deputy director of the Center for Developmental Biology (CDB) at RIKEN in Kobe, Japan, and coauthor on two recently retracted Nature papers about a reportedly easier way to make induced

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Interview with StemCells Inc. leadership on hot topics

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GregSchiffman

StemCells Inc. is a top biotech company developing stem cell-based therapies. They have a deep pipeline that includes already ongoing trials for a variety of diseases. I invited company leadership to do an interview and they graciously accepted. Below is the interview with CFO Greg Schiffman (picture at left from LinkedIn) including what I thought

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Multi-Billion Dollar NIH Brain Initiative A Stroke of Genius or Madness?

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Is the new multi-billion dollar NIH Brain Initiative a stroke of madness or genius? For some non-brain researchers scrambling for funding from NIH, it could well just give them a stroke. At the same time as the NIH and Obama are asking for $4.5 billion (yes, with a b) for the new “big science” Brain

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Arthur Caplan Article on Bogus Stem Cell Research: Some Different Views

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When bioethicist Arthur Caplan talks about stem cells, people pay close attention and for good reason. Caplan has provided important perspectives on the stem cell field over the years. For example, you can see a guest post on this blog here about human cloning. However, in my post today I respectfully discuss how I disagree with several parts of this week’s piece by

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Great News: Senators Boxer & Kirk Introduce Regen Med Bill

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I just heard some very good news on the regenerative medicine front, a new Regenerative Medicine Bill. US Senators Barbara Boxer and Mark Kirk today introduced The Regenerative Medicine Promotion Act, which would keep track of and promote regenerative medicine efforts. This is really exciting and provides hope. One of the neat things about this

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