Search Results for: embryonic stem cell

New Republican Governors Start Attack On Most Promising Stem Cell Research

Last Fall’s mid-term election brought into office several new Republican Governors who during their campaigns used strong, anti-embryonic stem (ES) cell research rhetoric. For example, then candidate for Governor of Wisconsin, Scott Walker (now the Governor) used some of the strongest language, which was ironic considering that human ES cells were first produced in Wisconsin

New Republican Governors Start Attack On Most Promising Stem Cell Research Read More »

Stem Cells in Wonderland

The-White-Rabbit-from-Alice-in-Wonderland

In Lewis Carroll’s masterpiece, Alice in Wonderland, there is a wonderful passage that came to mind as I read the latest response from the self-proclaimed ‘adult stem cell researchers’ suing the government to stop federally-funded ES cell research: “I don’t know what you mean by ‘glory,’ ” Alice said. Humpty Dumpty smiled contemptuously. “Of course you

Stem Cells in Wonderland Read More »

iPS cells coming into focus: not quite so similar to ESC after all

FaviconIPSCELL

Update in 2020: It seems now after all these years that the consensus in the now more mature field is that IPSCs and ESCs are nearly identical in most cases, and both have some of the same translational challenges such as teratoma-forming activity. It’s interesting to read this post from nearly 10 years ago and

iPS cells coming into focus: not quite so similar to ESC after all Read More »

Beyond naming: embryo models and the importance of public dialogue

mouse embryo models, human embryo models

Who decides what to name something new in science like “human embryo models”? Also, not to get too philosophical right off the bat, but what is the point of a name? It’s about a shared understanding of what we’re talking about. But, very often, both out in the world and in the various fields of

Beyond naming: embryo models and the importance of public dialogue Read More »

Recommended reads: Shinya interview, MYC-MAX & extra digits, microglia as a therapy, oocyte maintenance

N-myc, heterochromatin

The proto-oncogene MYC is one of those factors studied in thousands of papers. MYC and its dimerize partner MAX are also seemingly involved in just about everything. They have crucial roles in many kinds of stem cells including adult and embryonic stem cells. One way or another MYC induction seems very helpful for cellular reprogramming

Recommended reads: Shinya interview, MYC-MAX & extra digits, microglia as a therapy, oocyte maintenance Read More »

Weekly reads: diabetes, GvHD, Novo Nordisk & regenerative medicine, HDACs

mesenchymal cells

Do many in the regenerative medicine field have favorite types of stem cells? Some seem to think there’s a tension between those working on pluripotent stem cells like iPS cells and those working with MSCs. I don’t see it that way, though. Whatever stem cells work best for a particular condition should be used and,

Weekly reads: diabetes, GvHD, Novo Nordisk & regenerative medicine, HDACs Read More »