Search Results for: embryonic stem cell

Weekly reads: AL embryos ruling, blasting cancer, marrow organoids, beef inside rice plants

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Are small clusters of cells that make up 5-day-old human embryos equivalent to children? Biologically and in terms of just common sense, the answer is “no.” These tiny spheres have around 100 cells and no organs. Actual people have many trillions of cells, brains, and other organs. Alabama law on embryos may block IVF About […]

Weekly reads: AL embryos ruling, blasting cancer, marrow organoids, beef inside rice plants Read More »

Weekly reads: Xist & autoimmune disease in women, Crohn’s disease, dumb headline of the week

Xist ,auto immune disease

Readers of The Niche have asked me many questions about stem cells for autoimmune disease but the puzzle of why women get these conditions more often than men hasn’t come up before here. For instance, why is MS so much more common in women than men? It’s remained somewhat of a mystery over the years.

Weekly reads: Xist & autoimmune disease in women, Crohn’s disease, dumb headline of the week Read More »

Weekly reads: game of clones, super-SOX, Moonwalk Bio, Great Wall’s living skin

dog clones

I’m trying to remember the first time I ever heard about clones. It had to be as a kid. Maybe in a monster movie or TV show? Possibly a clone was referred to by the more general term “double”, which is not necessarily a clone. Whatever it was, I’m sure as a kid that I

Weekly reads: game of clones, super-SOX, Moonwalk Bio, Great Wall’s living skin Read More »

Review of Docere Clinics run by Harry Adelson including total-body injections

Amy Killen, Docere Clinic

In today’s post, I reviewed a stem cell clinic firm called Docere Clinics. In my opinion, there are some concerning issues here and reasons for caution. One type of procedure at Docere is particularly surprising and raises risks in my view. What is Docere Clinics? | What kind of stem cells does Docere use? | What they

Review of Docere Clinics run by Harry Adelson including total-body injections Read More »

Weekly reads: gene therapy nod, Nature pub ethics, CRISPR LDL

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Totipotency literally means all powerful, but it refers in biology to specific cells. These cells can make every type of cell in the body of an organism plus the extraembryonic tissues needed for development. This includes humans. So if you could reprogram human cells like blood or skin cells into totipotent stem cells, you might

Weekly reads: gene therapy nod, Nature pub ethics, CRISPR LDL Read More »

Weekly reads: Macchiarini pub, cloned journal, Mammoth genome, tweet of the week

Paolo-Macchiarini

Remember Paolo Macchiarini, the famous-turned-infamous so-called “stem cell surgeon” who ended up in legal trouble and with trial participants who died? Before we get into this we have a new feature for our weekly reads, which is the stem cell and regenerative medicine tweet of the week. See that at the bottom of the post.

Weekly reads: Macchiarini pub, cloned journal, Mammoth genome, tweet of the week Read More »

Weekly reads: reprogramming aging, astrocytes, cartilage, ChatGPT

Let’s start with a couple of new pieces on in vivo reprogramming. The idea here is to do something like making iPS cells but doing it inside organisms and not quite pushing cells all the way back to pluripotency. Just younger, healthier cells. Why do that? The goal is to achieve a kind of anti-aging

Weekly reads: reprogramming aging, astrocytes, cartilage, ChatGPT Read More »

Weekly reads: fibroblasts, gene-editing, Mitalipov, personhood, embryos

NIH 3T3 fibroblasts ATCC

I have a soft spot for fibroblasts, perhaps because one of the first immortalized cell lines I ever grew was NIH3T3. These are mouse fibroblasts that have been immortalized. They are very useful for a variety of experiments. I used them to study an oncogene called E2A-PBX1. Experience with fibroblasts including 3T3s I was amazed

Weekly reads: fibroblasts, gene-editing, Mitalipov, personhood, embryos Read More »