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Small umbilical cord stem cell COVID-19 trial: sign of efficacy?

stem cells for autism

A new paper today in Stem Cells Translational Medicine on a small COVID-19 Phase 1/2a trial using an umbilical cord stem cell product reports a surprising degree of possible efficacy. What’s the scoop here and could there be some hype in the media about this new study such as one of the authors describing the

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Our Educational Mission on The Niche Stem Cell Site

KnoepflerStemSymbol

Our mission here on The Niche is primarily educational. We aim to make a transformative difference in educating readers across the globe about stem cells, regenerative medicine, and innovative biomedical science more generally including CRISPR gene editing. A major part of that mission involves fact-checking various medical claims about stem cells and other biologics like

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Recommended stem cell reads: retractions, aging, COVID, CRISPR soldiers

lu et al nature eye regeneration

This week we have some interesting new reading including both on the stem cell basic and translational fronts as well as on COVID-19 vaccines. COVID-19 vaccine considerations From Derek Lowe at In The Pipeline on COVID-19 vaccine expectations at Science Translational Medicine, Get Ready for False Side Effects. You can read my views on possible

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More Duke Autism Center backstory: stem cell ‘magic’ & money

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Last week I wrote a long post detailing the troubling multimillion-dollar reverberations between the Duke Autism Center and a for-profit stem cell clinic. The clinic in Panama is The Stem Cell Institute. The potential entanglements raise a bunch of questions and concerns. They center on questionable, unproven autism “treatments”. In Duke’s case, their own clinical

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Overview of IPS cell prospects for clinical impact

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IPS cell research is a growing area of promise for regenerative medicine. These stem cells, also known as iPSCs or more formally as Induced Pluripotent Stem Cells, are engineered cells that are programmed to function the same way as embryonic stem cells. They can be differentiated into possibly any type of cell that is needed for

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FDA OK’s more COVID-19 efforts of unproven stem cell clinics

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In my view, it seems likely that the FDA has opened a big can of worms by starting to clear the COVID-19 trials and programs of for-profit stem cell clinics and other related firms. OK to Stemedica trial The FDA just approved another such effort, this one by the firm Stemedica. You can read more about

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Recommended reads: Bee brain, COVID, from Russia with stem cells, pubs

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Reading to them was one of my favorite things to do with my kids when they were little, but it’s a long way from Goodnight Moon to this week’s list of recommended reads, although “bee brain” may have got their attention. Please take a minute to complete our The Niche reader survey for a chance

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CAR-T cells review: cancer & a critical look at possible uses in aging & COVID-19

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Introduction to CAR-T cells CAR-T cells are an exciting cutting-edge technology that has been garnering great interest including in the stem cell field. Potential therapeutic uses of CAR-T, which stands for Chimeric Antigen Receptor T-Cells (CAR-T), are being studied in clinical trials as immunotherapies to potentially fight cancer as well as many other diseases by

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