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Our new paper assessing trials of cell therapy for COVID-19

stem cells for covid 19 kim knoepfler 2021

After the COVID-19 pandemic started clinical trials quickly sprouted up to test various kinds of cell therapy for COVID-19 including stem cells. The most common rationale for this approach is to suppress damaging overactive immune responses. Trials of cell therapy for COVID-19 including stem cells I’ve written quite a lot about these cellular medicine and […]

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Weekly stem cell reads: Pew, cord cells for COVID, more

large b cell lymphoma

Sometimes the recommended weekly stem cell reads are just a bunch of papers I find intriguing, but more often they include at least one or more things that are not necessarily “recommended”. Instead these are items that stimulate discussion and debate. Today’s post includes one such complicated area on cord MSCs related to COVID-19 plus

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Duke & Cryo-Cell plan big clinic for unproven infusions of kids

cryo cell duke stem cells autism cp

Professor Joanne Kurtzberg’s clinical work at the Duke Autism Center on umbilical cord blood for autism and cerebral palsy (CP) involves a partnership with a publicly-traded cord blood banking firm called Cryo-Cell. Kurtzberg is also the Medical Director at the firm. In addition they have intellectual property in this area. The Duke team’s efforts, including

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Weekly reads: cancer stem cells & other pubs plus a puzzler

kyu yum nature cancer stem cells niche

Cancer stem cells are one of the most interesting areas of research, intersecting the stem cell and cancer fields. Today’s weekly reads post highlights some new cancer stem cell articles along with some other interesting papers. I also note a recent weak stem cell clinical trial paper that is not a recommended read but is

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US Stem Cell clinic loses appeal, could impact pending Cali case?

us-stem-cell-clinic

The FDA filed two suits against unproven stem cell clinic firms in 2018 seeking permanent injunctions against them including US Stem Cell in Florida and Cell Surgical Network, et al. here in California. There’s been a major new development in this story that I see as good news. Court rejects US Stem Cell clinic appeal

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Cord conflicts at the journal Stem Cells Translational Medicine

stem cells for autism

The journal Stem Cells Translational Medicine has a long track record of publishing great work. I also have a lot of respect for the editors there and I’ve published there myself. But a few recent events have sparked concerns including over possible undisclosed conflicts of interest in some papers there about cord blood for autism.

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Weekly reads: court case, cancer stem cells, skin, pluripotency, & more

chen et al fig 1e nat comm 2021 phc1

This was a busy week for me working on a grant due Friday and a bunch of other stuff including happily analyzing a bunch of data, but there were tons of interesting papers recently including on pluripotency. California stem cell clinic court case on in the background Along the way this week I was occasionally

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COVID Traps Alveoli Cells in a Curious Progenitor State, Squelching Lung Regeneration

normal lung alveoli indicating examples at1 and at2 cells

Mere weeks into the COVID pandemic, stunning graphics began to appear depicting the path of devastation of SARS-CoV-2 through a human lung. It’s only recently that we’ve come to understand what, exactly, is happening on a cellular level. The new view is thanks to single-cell RNA-sequencing, which analyzes the abundance of messenger RNAs in individual

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