Search Results for: organoids

If I only had a brain: brain organoids from pluripotent stem cells

In a first for the field, scientists have used human pluripotent stem cells to grow miniature brain-like structures (brain organoids) in a dish in a lab (see beautiful image of one of these “mini-brains” at left from the paper). This exciting, pioneering feat, accomplished by a team from the Austrian Academy of Science in Vienna …

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Weekly stem cell reads: aging & cells, iPS cell mutations, gut, more

Stem cells aging

Does aging do something to time so it seems like as you get older that time goes by faster? Remember as a little kid when summer seemed to last forever and car rides could be agonizingly long? I’ve heard two theories on this. One is that the brain’s baseline of activity slows down with aging …

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‘We don’t want to freak people out’: about that Jacob Hanna human embryo model startup

Jacob Hanna Renewal Bio

Stem cell biologist Jacob Hanna has a new startup called Renewal Bio. Its goal is to harvest cells or tissues from human embryo or fetus models for clinical use. I believe that their commercial ambitions have so far outstripped careful thought and discussion in the broader community of researchers. There are major risks here for …

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Weekly science reads: Macchiarini trial, somites, CRISPR babies

organoids with somites, cool science

This has been one of those weeks where I spent some time thinking about taking risks in science. How much risk one should take? Risks can come in many forms. It could be at the core level at the bench doing specific experiments and not others. There’s risk in clinical trials, and even in advocacy. Sometimes …

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Weekly reads: fibroblasts, cancer stem cells, Parkinson’s

fibroblasts stained

It seems like the field of cell biology has mixed feelings about fibroblasts so I’m going to start off there with the recommended reads. But first, check out our stem cell YouTube channel as we are steadily heading toward 500 subscribers and 30,000 views. Please subscribe. I’ve pasted one of our top videos below, which …

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Stem cell therapy for heart disease: what you need to know

stem cell therapy for hearts

How much promise is there today for stem cell therapy for heart disease? Where do things stand with the clinical research? Patients regularly ask me these kinds of questions. The goal of today’s post is to update you on where things stand. What’s in this post Stem Cell Therapy | Clinical Trials | Delivery of …

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Hub of Regenerative Medicine & Stem Cell Meetings 2022

stem cell meetings 2022

Science must go on and so must stem cell meetings in 2022 with all those great conferences out there, but hopefully this year will be better than 2020-2021. It seems that way with the pandemic easing in the U.S. and many other places. On the other hand, COVID is spiking in Asia and other regions. …

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What is Matrigel, why a shortage, & alternatives?

Matrigel

Stem cell research relies on some unusual reagents at times including a cell culture product called Matrigel. One of the challenges with such reagents is that if they suddenly are back-ordered it could bring some research to a halt. Matrigel has been in short supply for the last year or so. These products also tend …

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Weekly reads: CAR-T cell good news, Califf fight, stem cells on lymph

CAR-T-cell-infographic

Not everything in biomedical science is a ground-breaking discovery or clinical game-changer, but CAR-T cell technology is a combination of both. CAR-T cell good news We have such good news in this new pub on long-term benefits: Decade-long leukaemia remissions with persistence of CD4+ CAR T cells, Nature. Another recent CAR-T cell article, this one in Science, …

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Recommended reads: senolytics, cow iPS cells, big CIRM royalty

Senolytics Steve Horvath

When we hear the word senile we might think stereotypically of an older person who has cognitive impairment, but some argue that senility can apply to cells too as they age and that such cells can be targeted by drugs called senolytics. Unfortunately, the supplements industry has picked up on this idea to sell iffy …

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