Search Results for: rmat

Weekly reads: Orchard punts on life-saving SCID trial, cardioids with cavities, more

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cardioids stem cells

Sometimes things in the stem cell world get complicated and this week is no exception with news of Orchard Therapeutics dropping a seemingly life-saving clinical trial. There are hundreds of kids who could possibly benefit. Rotten apple decision from Orchard Therapeutics From David Jensen at California Stem Cell Report we have something of a scoop: […]

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Cord conflicts at the journal Stem Cells Translational Medicine

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stem cells for autism

The journal Stem Cells Translational Medicine has a long track record of publishing great work. I also have a lot of respect for the editors there and I’ve published there myself. But a few recent events have sparked concerns including over possible undisclosed conflicts of interest in some papers there about cord blood for autism.

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When does a human embryo model become the real thing & other tough questions for a new field

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human embryo model mukul tewary sm

A human embryo model is a laboratory-produced collection of living cells that has some key things in common with real human embryos. They are made from pluripotent stem cells, which include embryonic stem cells and induced pluripotent stem cells or iPS cells. This research is both exciting and ethically complicated, raising some difficult questions. Embryo

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Weekly reads: oncodevelopmental factors, iPSC cancer vaccine, more

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stem cell vaccine paper ouyang et al

One of my main research interests is in oncodevelopmental factors. These include factors that are important both for normal stem cell biology and development as well as driving cancer when misregulated. One example includes the MYC family of proto-oncogenes. When I was a postdoc I got especially interested in trying to understand the normal role

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Ukraine clinic seems to backpedal from CRISPR people idea

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medeus clinic doctors. their recruitment emails had suggest a goal to crispr people for trait enhancement.

I wrote earlier this week about Medeus clinic in Ukraine seemingly trying to recruit genetics researchers to CRISPR people for trait enhancement. Aiming for CRISPR people with trait enhancement? In the recruitment emails they sent out it seemed fairly clear that they were planning to do CRISPR on people somehow via stem cells. They mentioned

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Ukraine clinic plans to sell CRISPR enhancements: hair color, skin, & breast size

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medeus clinic crispr enhancements

It was a couple of years back that researcher He Jiankui claimed he made three “CRISPR babies.” No one would think about doing any kind of rogue gene-editing again, right? Not even somatic gene edits. After all, as far as we know he’s in jail. We still don’t know the health risks that these three

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Cell and gene therapy products: what is an ATMP?

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atmp therapy

If you were to see the phrase ‘Advanced Therapy Medicinal Product’ (ATMP) you might guess, ‘an advanced treatment that is a medicine?’ but you will not get much more from this without doing a lot more homework. What is an ‘Advanced Therapy Medicinal Product’ or ATMP? Whoever decided that cell and gene therapy products should

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Weekly reads & stem cell news: New York axes NYSTEM, fetal tissue rules reversed, pubs & more

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stem cell book

It’s been a week with a wide variety of regenerative medicine papers and stem cell news. Here’s my earlier take from a few days ago on the Belmonte-led human-monkey chimeric embryo paper in Cell that broke this week. A few days ago I also put up a new video on our Stem Cell YouTube Channel

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As Neuroskeptic blog ends, reflections on skeptical science blogging

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skeptic magazine science blogging

It seems like being somewhat skeptical would be an inherent part of being a biomedical scientist. But not always it seems. On the other hand, some of us take it to another level by science blogging out our skepticism about certain topics. Note that there’s something called the Skeptics Society that publishes a magazine Skeptic.

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