Search Results for: sickle cell

Weekend reads: stem cells, organoids, cancer, CRISPR & a tiger named Igor

Tiger

What are your typical weekend reads? If you are a scientist, they might often include a great deal of science. I always hope I can find time for reading for pleasure too, but about as close as I get to that is the New York Times on Sunday. Here are some recommended science reads for […]

Weekend reads: stem cells, organoids, cancer, CRISPR & a tiger named Igor Read More »

Keys to successful stem cell translation – Nurses, physicians and patient advocates

Adrienne-Bell-Cors

Editor’s note: this is a guest post on stem cell translation. By Heather Main I recently attended the UCSD Health CIRM Alpha Stem Cell Clinics Network Symposium at the Sanford Consortium, San Diego. There was of course some great academic research presented, including conflicting views on liver stem cell compartments from Roel Nusse and David

Keys to successful stem cell translation – Nurses, physicians and patient advocates Read More »

Weekly reads: Vertex & CRISPR Therapeutics, Arnold Caplan death, MS genetics

CRISPR Therapeutics

The biotechs Vertex and CRISPR Therapeutics have an interesting relationship as biotechs. They are partners are multiple levels but also are very different as companies including in size. There’s been a key development in one of their partnerships. Before we jump into that, please check out the video version of my 20 stem cell and

Weekly reads: Vertex & CRISPR Therapeutics, Arnold Caplan death, MS genetics Read More »

New Year’s reads: having a blastema, gene therapy cost, pathogen lab escape data

blastema

Years ago I wrote about how I wished humans could form a blastema, which is a special area of regeneration near an injury that drives tissue replacement. For example, when a lizard loses its tail to a pursuing bobcat, if it can regrow a new one that process will depend on a blastema. The same goes

New Year’s reads: having a blastema, gene therapy cost, pathogen lab escape data Read More »

Weekly reads: clonal expansion, Golden Retriever cancer, FTC hits genetics firm on testi-phony-als

clonal selection

Let’s start this week’s digest with a discussion of clonal expansion and mutations during cell and gene therapy development. Here’s the article that brought this to mind. Sickle cell gene therapy process may cause cancer-linked mutations in blood stem cells, Fierce Biotech. Clonal expansion This is a story about a non-CRISPR gene therapy using a

Weekly reads: clonal expansion, Golden Retriever cancer, FTC hits genetics firm on testi-phony-als Read More »

Weekly reads: Verve Therapeutics, Casgevy UK OK, GDNF, MYC

Sekar Kathiresan, Verve Therapeutics

Some folks can view data from early, small clinical trials too skeptically or overly enthusiastically, and maybe that’s going on with some preliminary results from Verve Therapeutics. Good news? Bad news? I’m going to start with two articles about the same news that have very different vibes. What do I think? On the whole, I

Weekly reads: Verve Therapeutics, Casgevy UK OK, GDNF, MYC Read More »

Weekly reads: Mammoth De-extinction update, space babies, Alzheimer’s, MSCs don’t help knees

George Church De Extinction Mammoth

What’s more important than Woolly Mammoth de-extinction research in the stem cell arena? Only maybe a 10,000 other things. Still, the mammoth de-extinction efforts  capture people’s attention much more than the average research story. Mammoth De-extinction update Is de-extinction only a pipette dream? This startup has a big, expensive plan to find out, Popular Science.

Weekly reads: Mammoth De-extinction update, space babies, Alzheimer’s, MSCs don’t help knees Read More »

Weekly reads: UC Davis Medical School diversity, CRISPR, Parkinson’s

UC Davis Medical School

It’s been almost seventeen years that I’ve been a professor here at UC Davis Medical School. It feels like home. I enjoy teaching our first-year medical students each year. Some end up doing research in my lab. Our school recently got a nice write-up over at STAT News by Usha Lee McFarling on the diversity

Weekly reads: UC Davis Medical School diversity, CRISPR, Parkinson’s Read More »