Osiris, a cellular therapy biotech, recently received a so-called “untitled letter” from the FDA. The text of the letter seems on the whole negative in my opinion, while the company’s public reaction to the letter on the other hand could be seen paradoxically as rather cheery. What’s going on here? With Halloween coming, one has […]
Osiris FDA Letter: Trick or Treat? Read More »
When Jacob Hanna says “radically deterministic” cellular reprogramming, what does he mean? Jacob Hanna’s lab recently published a very high profile Nature paper on nearly 100% efficient iPS cell formation based on targeting a factor called Mbd3. This super efficiency is a major departure from past reported efficiencies. This morning here at the Till &
Jacob Hanna on Radically Deterministic Reprogramming @TMM2013 Read More »
What can clouds tell us about a stem cell legal court case strategy such as USA v. Regenerative Sciences? It turns out, quite a lot. In about a week a Federal Appeals Court Case will begin to review the ruling in the USA v Regenerative Sciences that favored the FDA. This is arguably one of
USA v Regenerative Sciences Word Clouds are Illuminating Read More »
How could there be a nose on top of head? We all have heard the expression “eyes on the back of one’s head”, but a nose on top of one’s head? What the heck? A Chinese doctor has apparently grown a new nose on top of a patient’s forehead. The patient had his nose damaged
Doc grows new nose on top of head Read More »
A team at the Weizmann Institute of Science in Israel led by Jacob Hanna reports today near perfect reprogramming efficiency to make induced pluripotent stem cells (iPSCs) by eliminating a single factor called Mbd3 from the cellular equation. On first glance, the Nature article (Rais, et al.) seems to be all about boosting cellular reprogramming efficiency to close
100% reprogramming efficiency reports Jacob Hanna Read More »
Need a new liver, pancreas, or other vital organ, then I’ll 3D print one right up for you…that is in about 10 years. My intern Lakshmi did a great job on her guest piece last week on the promise of 3D printing in stem cell-based bioengineering including organ and tissue production. It’s an incredibly exciting area of
Want to 3D Print Yourself a New Organ? Key Challenges Read More »
Let’s putting on our “thinking caps”….er, extra brains, get our geek on, and have some fun imagining where stem cell technology may lead us in the coming century. Unhappy with the one brain you have? Wouldn’t it be amazing to have a 2nd one too? A new one? Researchers have grown mini brain-like structures from
What would you do with an extra brain? Read More »
Was Einstein wrong on his definition of insanity? “Insanity”, said Einstein, “is doing the same thing over and over again and expecting different results.” But in science, how sane is it to expect experiments to give precisely the same results? How big a problem is irreproducibility in science? Experiments on that question have given variable
Was Einstein Wrong About Insanity? Read More »
What’s the deal with IntelliCell Biosciences, headed up by Dr. Steven Victor? Sometimes science can move at warp speed and that is even more true of the stem cell field. One stem cell establishment that seems to be in a particularly intense period of activity and that has drawn a great deal of attention lately
Interview with Dr. Steven Victor of IntelliCell Biosciences (SVFC) Read More »
IntelliCell BioSciences, Inc. of New York, a clinical stem cell establishment, has had a rough time of it lately. For example, a recent piece of bad news is that there is an impending foreclosure sale of the company’s assets. What exactly that means for the company more broadly remains unknown, but a few people tell me (take this
New FDA IntelliCell BioSciences, Audit Report: A Lot of Work to Do Read More »