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Hateful politics infiltrate human genome editing debate in France

June 27, 2016 / Professor Paul Knoepfler, Ph.D. / 1 Comment

By Elliot Hosman Summary. A campaign calling for a moratorium on using CRISPR in human embryos was launched by a prominent French organization fighting for narrow understandings of life and family. A recent campaign calling for a ban on “transgenic” human embryos was launched by one of France’s most prominent organizations fighting for “science”-backed “one-man-one-woman” […]

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5 big picture stem cell trends at ISSCR 2016

June 26, 2016 / Professor Paul Knoepfler, Ph.D. / 3 Comments

Now that the ISSCR annual meeting is over, some overall stem cell trends are evident from the meeting in terms of the direction of the stem cell field. This was one of my favorite ISSCR meetings. Translation expectation and upbeat tone. The overall vibe at the meeting was a sense of excitement and optimism about the

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Shinya Yamanaka at ISSCR 2016 on reprogramming of cells & scientists

June 23, 2016 / Professor Paul Knoepfler, Ph.D.

The second day of ISSCR 2016 started off with a great session on pluripotency and plasticity, and the first talk was by Shinya Yamanaka. He changed the title of his talk to “Reprogramming of Cells and Scientist”. As with my other posts on this meeting, this one is a stream of quotes and impressions from

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The backstory on my opinion piece in SF Chronicle critical of CIRM lobbying

June 19, 2016 / Professor Paul Knoepfler, Ph.D. / 3 Comments

Today an opinion piece that I wrote about CIRM was published in the San Francisco Chronicle. The unusual element here is that the article is critical of CIRM. More specifically I raised concerns about a recent political trend at CIRM under its new President Randy Mills lobbying for dramatically weaker stem cell regulatory oversight. The Chronicle piece was first posted

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Stem cells for stroke hype analysis: 9 very different headlines

June 4, 2016 / Professor Paul Knoepfler, Ph.D. / 16 Comments

I wrote yesterday about two cases of science media hype on CRISPR and on stem cells for strokes. The latter case on stem cell hype stirred the most discussion and even some harsh words in the comments. As this stem cell stroke story on an encouraging but very small, preliminary study has unfolded across the

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UC Davis CRISPR meeting: Vital Role of Language in CRISPR

May 27, 2016 / Professor Paul Knoepfler, Ph.D.

Here is another of my blog posts from yesterday’s CRISPR meeting on ethics, science, and policy held here at UC Davis. You can read the others here, here, and here. Note as with the other posts, since I was taking notes as listening and on the fly, this post is a stream of consciousness on

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UC Davis CRISPR Meeting Panel: A View from the Trenches on Human Disease

May 26, 2016 / Professor Paul Knoepfler, Ph.D. / 3 Comments

The second session at our CRISPR meeting was really powerful. As with other posts from the UC Davis CRISPR meeting, since I was taking notes on the fly during this session, this post is a stream of bits from the different talks, often trying to capture the essence of key questions or ideas as the speakers

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UC Davis CRISPR Meeting: Big Picture from Ben Hurlbut

May 26, 2016 / Professor Paul Knoepfler, Ph.D.

The CRISPR meeting has started off wonderfully with a talk by Ben Hurlbut. His talk was entitled, “The Demands of CRISPR’s World: Imagination, Deliberation and Governance”. Since I took notes and listened this post is somewhat freeform. I liked how Ben asked a lot of questions. What is “CRISPR’s world” as Science Magazine called it? How

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Huge clinical trial fees allowed by FDA at times, details often secret

May 22, 2016 / Professor Paul Knoepfler, Ph.D. / 9 Comments

Why can there be huge clinical trial fees for participants? I am often critical of for-profit stem cell clinics on this blog for numerous reasons. For instance, one thing that concerns me greatly about these clinics is that they charge patients to get experimental “treatments” that have not been proven to be safe or effective. But

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TGIF Science: funding, CRISPR v. NgAgo, secrets, Zika, & more

May 20, 2016 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Some stuff on my mind for our TGIF Science this week. Research Funding Ups: NIH. Is it my imagination or is NIH funding slightly improving? This is the overall vibe I’m hearing from the trenches. Research Funding Ups and Downs: CIRM. CIRM funded some basic research to the tune of a total of $4 million,

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