Below is a conversation with bioethics commentator Kelly Hills (who BTW has a great blog), tackling some of the key issues surrounding the potential use of CRISPR-Cas9 technology to make heritable human genetic modification. I really appreciate her clear and insightful answers to some tough questions that many are grappling with today on this topic. Part […]
Kelly Hills interview: human genetic modification & bioethics Read More »
I’m doing a series of interviews with leaders in the field on human germline modification with the first interview in this series with George Church and today’s second in this series is a conversation I had with Dr. Jennifer Doudna, a pioneer in CRISPR-Cas9 technology. Doudna is a Professor in MCB and Chemistry as well
Jennifer Doudna Interview on CRISPR, Human Gene Editing Read More »
One of the most exciting developments in the biomedical sciences in 2014 was the announcement of the new Allen Institute for Cell Science. This new institute, which will be focused on cell biology, received $100 million in funding from high-tech pioneer and philanthropist, Paul Allen. I am very curious about how the institute will tackle cell
Horwitz Interview Zooms in on Allen Cell Institute: the GoogleMaps of Cells Read More »
The Niche is the top, most authoritative stem cell and regenerative medicine blog on the web and the only one to our knowledge written by a professor. It is mainly written by Professor Paul Knoepfler of UC Davis School of Medicine, an internationally respected stem cell biologist and educator. Knoepfler is an advocate of rigorous
About Us, The Niche and Knoepfler Lab Read More »
It was my pleasure recently to talk at length with Dr. Michael West, CEO of the Stem Cell Biotech, BioTime (BTX). West has been at the helm of BioTime since 2007 and is a true pioneer in the stem cell field. He founded Geron (GERN) and was a top leader at Advanced Cell Technology (ACT; stock
Interview with BioTime CEO Michael West Part 1: a little stem cell history Read More »
I have an ongoing poll on people’s impressions of the big annual stem cell meeting, ISSCR 2012. I myself have been wishing I was in Japan for that meeting so I remain surprised at the trending of the poll toward the negative. By far the most common response has been a surprisingly ho-hum “so-so” evaluation
Wish list from 2012 attendees for ISSCR 2013: some crankiness Read More »
For a few years, biophysicist He Jiankui might have been one of the most recognizable scientists on the planet. He made three “CRISPR babies” or gene edited people. However, his gene editing went badly and as best as we can tell his efforts did not result in precision edits. It’s unclear if he had institutional
The Parent’s Guide to Cord Blood Foundation recently announced that Cryo-Cell and its long-time partner, a Duke pediatric cell therapy team, have made a key change. They will begin offering infusions of unrelated, unproven cord blood to pediatric patients with cerebral palsy (CP). These are called donor infusions. Up until now, they had mainly focused
Joe Rogan just keeps glowing about clinics offering unproven stem cells like most recently the Cellular Performance Institute in Tijuana. Often Joe talks about his own experiences getting stem cells, but other times he refers anecdotally to others who supposedly had great experiences. While it’s not unusual for some celebrities to get stem cells at
Joe Rogan shows more love for unproven stem cells despite risks Read More »
New research on stem cell patches is exciting. However, more broadly, “stem cell patches” can mean very different things. What I’m talking about here are the types of patches that can repair holes or other problems with tissues. This is a powerful regenerative approach. In contrast, I’m not a fan of the type of stem cell
Weekly reads: stem cell patches, helicase editing, hearing loss, Astellas, Dr. No Read More »