CIRM has reinvented itself in a new form, CIRM 2.0, under the leadership of its new President Randy Mills. CIRM is almost like a stem cell that has changed into another new kind of stem cell. Us scientists could see the change coming in the “programming” at CIRM in terms of how it was operating as …
As CRISPR gene editing technology has advanced in the last few years, the number of genetically modified animals made with this system has steadily increased. Some are very interesting and useful for science. At the same time especially when they are little, they can be very cute. A nickname is going around for these GM …
CRISPR critters: Cute pics of Cas9 gene edited animals Read More »
Many of us scientists, ethicists, and legal scholars are working on educational outreach to the public on the potential use of gene editing technologies like CRISPR to genetically modify human beings, but clearly there’s a long way to go and much more to do on this front. By the way, you may find this new …
Public polling on human gene editing, moratorium Read More »
A decade ago I wrote an article in the journal Nature Biotechnology about the rise of a new gene editing technology called zinc finger nucleases (ZNF). It was one of those “drumbeat” discoveries: at the time, my sense was it would revolutionize how we deliver genes to cells and tissues, and profoundly change the way …
Guest Post by Chris Scott–The Great CRISPR Controversy: What’s Next? Read More »
What is the “proper” amount of freedom of choice for patients in medicine? What if the treatments in question are experimental and come with their own baggage of associated risks, personal costs, and potential costs to society? More broadly, do patients have a fundamental right to medical choice? These questions seem particularly appropriate today on …
Statins have been hailed as some of the best drugs ever. Given the massive, deadly prevalence of cardiovascular disease, some have even semi-jokingly talked about putting these drugs in the water supply for public health. The growing evidence (e.g. this story) that statins might significantly aid in prevention, delayed progression, or even post-treatment delay of …
Statins dilemma: heart & cancer benefits, but diabetes risk Read More »
Later this May, I will attend and participate in Biotechnology and the Ethical Imagination (BEINGS 2015). This is an exciting and experimental summit that will focus on advances in cellular biotechnology – including both stem cell science and synthetic biology. The meeting is premised on the idea that the implications of increasing biotechnology power are …
Biotechnology & the Ethical Imagination – A Preview of BEINGS summit Read More »
Last week was a big one for the life sciences in that we saw the milestone of the first ever published paper reporting human embryo genetic modification (see here and here). It was one of those situations where we knew it was coming, but it was still a jolt. Not surprisingly this event sparked intense discussion …
4 areas of debate on 1st human embryo genetic modification paper Read More »
The paper that came out Wednesday from a research group in China reporting the first genetic modification of human embryos has sparked a lot of discussion. Some concerns about this paper have surfaced. 2-day review? The paper (HT to John Borghi) was in review only from March 30-April 1 — so at most 48 hours. Really? That certainly …
Concerns surface on Chinese paper on genetic modification of human embryos Read More »
Rumors have been flying for months that researchers in China and possibly elsewhere were shopping papers around at high-profile journals that reported gene editing and genetic modification of human embryos. Update: apparently this paper (HT to @JohnBorghi) was only reviewed for 2 days (see image at bottom of post), raising major concerns about the depth of …
Researchers in China make genetically modified human embryos Read More »