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TGIF: recommended weekend science reads & a jar full of RNA

August 14, 2015 / Professor Paul Knoepfler, Ph.D.

TGIF recommended weekend reads including thought-provoking reading over a beer, glass of wine, or beaker…and what would RNA taste like? Two from Alexey Bersenev The future of human limb bioengineering Translating Cell Therapies: Academic versus Industry model CIRM blog: two cool recent posts Specialized Embryonic Stem Cells Yield Insights into X Chromosome Inactivation Da Mayor and […]

Why interview Steven Pinker on my blog if I strongly disagree with him?

August 13, 2015 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Earlier this week I posted an interview with Steven Pinker on CRISPR, human germline modification, and bioethics. With only a few exceptions, I strongly disagree with Pinker’s philosophy in these areas and I knew going into the interview that his answers would likely go against my own views. I also expected the interview would anger

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Exciting CRISPR-powered “gene drive” also has scientists deeply concerned

August 12, 2015 / Professor Paul Knoepfler, Ph.D.

Scientists studying genetics are both excited and worried about a powerful, new technology called “gene drive“. Some have been raising serious concerns about gene drive and in certain cases calling for proactive regulation, which is unusual in science. This method is so powerful because it is designed to induce genetic changes in an entire population

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Steven Pinker interview: case against bioethocrats & CRISPR germline ban

August 10, 2015 / Professor Paul Knoepfler, Ph.D. / 15 Comments

CRISPR-Cas9 gene editing technology is red-hot right now and I’ve been doing interviews with various thought leaders on it, which today includes Steven Pinker. This technology has great power for research in the lab and there are hypothetical transformative clinical applications of CRISPR too. The latter efforts could include experimental attempts at reversal of disease-causing

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Global transhumanism leader Natasha Vita-More on human germline modification

August 3, 2015 / Professor Paul Knoepfler, Ph.D. / 1 Comment

In my continuing series of conversations with thought leaders related to heritable human modification, today’s post is an interview with Natasha Vita-More, a pioneer in the transhumanism movement and Chairman of the Board of Directors of Humanity+ (H+), the global transhumanist organization. Where do you see transhumanism today? Has it changed over the years? What

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TGIF: Recommended Science & Medicine Weekend Reads

July 31, 2015 / Professor Paul Knoepfler, Ph.D. / 4 Comments

With these recommendations I’m aiming for a diverse range of content and perspectives, some of which I may not agree with, but all of which are interesting even if they are beyond research on medicine. Prostate Organoid from Stem Cells. More organoid news. Why Do Glowing Sharks Glow? Not exactly medicine, but a cool piece

Fantastic organoid voyage: views from inside organoids

July 30, 2015 / Professor Paul Knoepfler, Ph.D.

The classic sci-fi movie Fantastic Voyage keeps coming to mind for me as I see and do research involving organoids. In it, the heroes travel inside of the human body in a craft, observing all kinds of awesome biology in an up close and personal kind of way on route into the brain with the goal

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Scientists and suicide

July 26, 2015 / Professor Paul Knoepfler, Ph.D. / 5 Comments

Why do some scientists commit suicide and can such suicides be prevented? Clearly it can be hard or even impossible to tell from the outside what things may be like on the inside for anybody whether they are a scientist or not. Last year the world of science, and in particular the stem cell and

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Perspectives on Planned Parenthood Fetal Tissue Video

July 20, 2015 / Professor Paul Knoepfler, Ph.D. / 5 Comments

You probably have heard by now about the controversial video (below) showing the senior director of medical services of Planned Parenthood, Deborah Nucatola, discussing the procurement and distribution of fetal tissues from abortions for research. The film was taken secretly using a hidden camera by anti-abortion activists who concealed their real identities. It was edited

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Huge Hack at UCLA Health: Millions of Patients’ Personal & Medical Data Compromised

July 17, 2015 / Professor Paul Knoepfler, Ph.D. / 2 Comments

On May 5 UCLA Health System determined that its computer systems had suffered a massive hack. The cyber attack compromised the data of millions of UCLA patients according to the University: “the attacker had accessed parts of the UCLA Health network that contain personal information, like name, address, date of birth, social security number, medical

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