Month: March 2011

Secret Not so Secret Recipe for Safer iPS cells

IPS cells, induced pluripotent stem cells, Knoepfler lab, stained for TRA-1-60, an ES cell marker., where do stem cells come from?

Just how tumorigenic are iPS cells?  The field really doesn’t know at this point. However, a steady stream of papers have raised red flag after red flag about genomic and epigenomic alterations/mutations that are linked to cancer. Of course, then there is the fact that all the genetic changes actually used to make reprogrammed cells …

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Opposing stem cell research is unpatriotic

I have an op-ed piece in today’s Sac Bee.  You can read it here. In the piece I highlight the amazing promise that stem cell technology holds for treating our wounded soldiers on the battlefield. I focus on the life saving areas of stem cell derived blood, spinal cord injury treatments, orthopedic injuries, and burn …

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New papers support growing serious safety concerns about iPS cells

A growing body of evidence has convincingly argued that iPS cells contain numerous abnormalities at the genetic and epigenetic levels. Often these changes have links to the machinery in cells that is responsible for cancer. As a result, many in the stem cell field have raised the notion that iPS cells may never be able …

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