September 29, 2020

The Niche

Knoepfler lab stem cell blog

In Bart Starr stem cell treatment for stroke, following Howe to Mexico?

Bart Starr, stem cells
Bart Starr apparently got unproven stem cells.

NFL Hall of Fame player Bart Starr has reportedly turned to stem cells for hope after having a series of strokes in 2014.

The Starr family made a statement that Bart, now 81 years old, was accepted into a clinical trial using stem cells.

This seems similar to the stem cell path that the family of hockey legend Gordie Howe took following his strokes last year. Gordie just got a second treatment this year apparently. You can read about Howe’s treatment and that complicated situation in a number of articles here.

Although no further details were noted on Starr’s treatment, it seems likely that the Starr family have connected with the controversial (e.g. see critical pieces by Science-Based Medicine here) stem cell company Stemedica, which gave Howe non-FDA approved stem cell interventions in Mexico through its partner Novastem. Why do I think that is likely? In a recent news article on the Stemedica-Howe case, it was noted that the Starr family had contacted Stemedica too.

Assuming he received the same Stemedica/Novastem therapy as Howe, Starr would have gotten infusions of both adult stem cells and fetal stem cells. Note that it is also possible that Starr did not receive treatment from Stemedica and Novastem, but rather in another clinical trial from some other entity. If I learn more, I will post updates.

One concern regarding Stemedica in the past has been that they mentioned to the media that they use adult stem cells. In USA Today, Stemedica’s Maynard Howe (no relation to Gordie) had this to say about their use of fetal stem cells:

“We don’t use the word fetal too much,” said Maynard Howe, Stemedica’s CEO, who is no relation to Gordie Howe. “We just don’t want to get people confused about what it is. They’re really considered legally adult stem cells even if they’re fetal-derived.”

This seems to muddy the waters and add to confusion by being vague. In my opinion, fetal stem cells are not adult stem cells. I realize that some may disagree with that. The main overall point is to use precision in talking about these therapies. I would also say that I am not necessarily opposed to the use of fetal stem cells in certain situations if there is concrete data indicating promising safety and efficacy profiles.

Notably, Howe received his stem cell treatment from Stemedica for free, which raises the question of whether Starr did as well.

Even though I have philosophical differences with Stemedica and Novastem, I understand and am sympathetic to patients and their families. They are looking for hope, especially with severe conditions like strokes.

I wish Bart and the Starr family all the best.

Below is the Starr family statement, which I find to be very positive in its clarity and the fact that they say that they will let the results speak for themselves:

“Following Bart’s strokes, our family began to investigate numerous therapy options. Several months ago we applied for and were accepted into a clinical trial using stem cells. Friday we safely returned home from the first of the two treatments.

“While we welcome everyone’s interest and support of Bart’s health, at this time, we’d like to allow him a chance to fully participate in the clinical trial and let the results, if any, to speak for themselves. At an appropriate time in the future, our family looks forward to sharing the details of Bart’s participation in this most important clinical exploration of what role stem cells may play in the treatment of stroke.

“Until then, we continue to thank you for all of your love and prayers. Your support has given us much strength over the past nine months. Bart joins me in sending our love and appreciation to all our special friends and fans. We are working hard toward the one goal he most cherishes: a return to Green Bay for a Packers game.”

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