2015

Weekend Reads: Cool Papers, PubPeer, Jacob Hanna, & More

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Here are some papers and news for weekend reads. What are you reading this weekend? What are your go-to stem cell journals? Hostile Takeover: Glioma Stem Cells Recruit TAMs to Support Tumor Progression by Yu Shi, Yi-fang Ping, Xia Zhang, Xiu-wu Bian in Cell Stem Cell. YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate self-renewal and […]

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How can baldness help cure kid’s cancer? St. Baldrick’s

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For the 4th straight year I’m going to get my head shaved to support St. Baldrick’s in their mission to cure childhood cancer. St. Baldrick’s is a great charity that raises money specifically for pediatric cancer research in part via events at which “shavees” raise funds via pledges that they will get their heads shaved.

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ARM Asks FDA for Clarification on Draft Guidance on Minimal Manipulation

Alliance-for-Regenerative-Medicine

In the last few months the FDA has taken steps toward crystalizing regulatory oversight of stem cell and more broadly cell and tissue-based therapies. These steps come in the form of several draft guidances  (see here, here, and here) . The Alliance for Regenerative Medicine (ARM) has responded to the draft guidance on Minimal Manipulation. For example, ARM has

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Are babies from same-sex couples possible?

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A question that has come up with advances in stem cell technology: could same-sex couples have their own biological children? Since Shinya Yamanaka reprogrammed first mouse and then human ordinary cells into powerful pluripotent stem cells, termed induced pluripotent stem (iPS) cells, back in 2006-2007 many new research avenues have opened up. The impossible suddenly

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ViaCyte CEO Laikind Interview: Trial Update, Melton, & Future

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It’s been exciting to watch the recent developments in using stem cells as the basis for treatments for Type I Diabetes. One of the major players in this arena is the privately-held company, ViaCyte. In this post, I interview ViaCyte President and CEO, Paul Laikind. The topics include their VC-01 product, the Encaptra device, an update on

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Monday, March 2: My Reddit AMA on 3-Person IVF – Mitochondrial Transfer

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On Monday, I’ll be doing another Reddit AMA, this time on 3-person IVF also known as 3-parent IVF, mitochondrial transfer, 3-parent babies, etc. You can see the upcoming AMAs including mine listed in the right sidebar here. Mine will start at 10AM PST/1PM EST. I hope to discuss with a wide audience all the key

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Supreme Court Rejection of WARF hESC Patent Challenge Discussion

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The challenge to the WARF/Jamie Thomson patents/IP on human embryonic stem cells (hESC) is at an end. The US Supreme Court declined to hear the case. Earlier, the USPTO had turned down the challenge leading to a winding road in the courts. What do you all think of this stem cell IP challenge and the

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