So everyone is buzzing about the CRISPR patent court decision (which BTW I think was flawed but that’s for another post), but the research roars on at warp speed.
Here are 7 recent CRISPR articles that caught my attention.
What are your favorite recent CRISPR papers?
Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration. Do you think the term “genome surgery” is appropriate?
Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells. CRISPR on the brain.
Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy. CRISPR pre-clinical promise.
The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia. CRISPR vs. cancer.
Expanding the CRISPR Toolbox: Targeting RNA with Cas13b. CRISPR systems continue to evolve.
CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells. CRISPR’ing ES cells.
Interspecies Chimerism with Mammalian Pluripotent Stem Cells. I blogged on this one here and did an opinion piece at WaPo here.
Stem cell therpy should be highly effective but the clinical trial will clear the facts.
Hi Dr. Knoepfler, thank you for the great sharing. I am a PhD student from Monash University Australia. I am working on CRISPR gene editing on human iPSCs to study kidney disease. Personally, I found it so fascinating yet overwhelming the field is moving so fast where I am just at the very beginning of the learning journey. Please continue to share the latest stem cells news and would love to hear your thoughts about the updates. Ricky