November 30, 2020

The Niche

Knoepfler lab stem cell blog

CRISPR

3 min read

How should we view biohackers and their DIY use of CRISPR outside of the traditional industry or academic lab environment? Introduction to “Biohackers” and DIY CRISPR Who are biohackers exactly? They are people who “hack” their own biology by transforming their bodies through the insertion of technology or modification of their DNA. More rarely, biohackers hack other people’s bodies, but that could change and become more common. In recent years, with the strides made in CRISPR technology, biohacking in genome modification has garnered much …Read More

3 min read

Maybe we can use science as an escape from politics during the last week or so before the election? I hope so. Here are my weekly recommended reads. Several papers ended up relating to nucleus, cell and embryo size and space as well as chromatin, which is very interesting. Cell and chromatin biology pubs, media Vast Self-Renewal Potential of Human AGM Region HSCs Dramatically Declines in the Umbilical Cord Blood, Stem Cell Reports DUSP16 is a regulator of human hematopoietic stem and progenitor cells …Read More

5 min read

CRISPR applications in the real world The “breakthrough” gene-editing tool, CRISPR Cas9, has been utilized for various purposes since its popularization and commercialization in the early 2010s. While possible uses of gene editing in humans tend to get the most attention, the application of CRISPR-Cas9 also encompasses the animal world and the analysis of a multitude of species from common livestock to exotic, wild animals. The use of CRISPR gene-editing in these animals involves constructing animal models for the research of disease mechanisms and …Read More

3 min read

As a researcher, is there ever enough time to get to everything that you want to read especially in newer areas like stem cells, organoids, and CRISPR, without even including non-scientific reads like Shakespeare or a new novel or something like that? Hopefully, putting together lists of recommended reads like today’s post is helpful. I wonder what Shakespeare would have thought about organoids? Media including COVID-19 updates Interesting change at Nature, which will be diving more into political coverage. Here’s their editorial on this …Read More