CRISPR

Ukraine clinic seems to backpedal from CRISPR people idea

medeus clinic doctors. their recruitment emails had suggest a goal to crispr people for trait enhancement.

I wrote earlier this week about Medeus clinic in Ukraine seemingly trying to recruit genetics researchers to CRISPR people for trait enhancement. Aiming for CRISPR people with trait enhancement? In the recruitment emails they sent out it seemed fairly clear that they were planning to do CRISPR on people somehow via stem cells. They mentioned …

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Ukraine clinic plans to sell CRISPR enhancements: hair color, skin, & breast size

medeus clinic crispr enhancements

It was a couple of years back that researcher He Jiankui claimed he made three “CRISPR babies.” No one would think about doing any kind of rogue gene-editing again, right? Not even somatic gene edits. After all, as far as we know he’s in jail. We still don’t know the health risks that these three …

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Recommended reads: CRISPR for Sickle Cell, Parkinson’s, & more

victoria gray family crispr sickle cell b

I’m playing catch-up on some reading given how busy I’ve been and this includes a groundbreaking NEJM pub on CRISPR for Sickle Cell and Thalassemia. CRISPR for Sickle Cell From December, here’s the key paper in the NEJM: CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia. There’s a lot to like about this clinical …

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Perspectives on Biohackers and DIY CRISPR

biohackers series sm

How should we view biohackers and their DIY use of CRISPR outside of the traditional industry or academic lab environment? Introduction to “Biohackers” and DIY CRISPR Who are biohackers exactly? They are people who “hack” their own biology by transforming their bodies through the insertion of technology or modification of their DNA. More rarely, biohackers …

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Weekly science reads: CRISPR, stem cells, cell size & space, more

DNA-origami-goniometers

Maybe we can use science as an escape from politics during the last week or so before the election? I hope so. Here are my weekly recommended reads. Several papers ended up relating to nucleus, cell and embryo size and space as well as chromatin, which is very interesting. Cell and chromatin biology pubs, media …

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CRISPR critters advancing science & agriculture

CRISPRd-goats-small

CRISPR applications in the real world The “breakthrough” gene-editing tool, CRISPR Cas9, has been utilized for various purposes since its popularization and commercialization in the early 2010s. While possible uses of gene editing in humans tend to get the most attention, the application of CRISPR-Cas9 also encompasses the animal world and the analysis of a …

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Weekly reads on organoids, COVID, CRISPR, cold chromatin, more

Cold-chromatin

As a researcher, is there ever enough time to get to everything that you want to read especially in newer areas like stem cells, organoids, and CRISPR, without even including non-scientific reads like Shakespeare or a new novel or something like that? Hopefully, putting together lists of recommended reads like today’s post is helpful. I …

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Can Gene-Edited Stem Cells Treat Cystic Fibrosis?

human-IPS-cells-made-in-Knoeplfer-lab-stained-for-TRA-160

Drugs that restore the shape of the errant protein behind cystic fibrosis (CF) have, over the past eight years, helped the majority of patients, who have certain mutations. Gene-corrected stem cells might offer a “mutation agnostic” option to CF. CF results from a glitch in a glycoprotein with the unwieldy name “cystic fibrosis transmembrane conductance …

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New research on CRISPR gene-editing in stem cells, infographic

CRISPR-infographic-stem-cells_small

As a pivotal advance in the gene-editing field and timeline, CRISPR continues to be utilized for research on stem cells and human diseases. Today, I will explain some of the most notable recent findings in the stem cell-CRISPR field. To start things off, I have also created an infographic that briefly explains what CRISPR-Cas9 is, …

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New human genome editing (HHGE) academy report: solid, but key gaps

The-International-Commission-on-the-Clinical-Use-of-Human-Germline-Genome-Editing-HHGE

Something called, “The International Commission on the Clinical Use of Human Germline Genome Editing” has issued a new report on heritable human genome editing (HHGE). The Commission was convened by the U.S. National Academy of Medicine, the U.S. National Academy of Sciences, and the U.K.’s Royal Society. This post is my initial take on the summary of …

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