Reviews of P shot & O shot stabs at sexual enhancement

Something called a P shot has sparked interest from some men interested in high-risk attempts at enhancement.

The goal of today’s review post is to fact-check P shots. They’re sold for supposed penis enhancement or to address erectile dysfunction (ED). I’ll also fact-check so-called O shot stabs at vaginal rejuvenation or enhancement.

These are both literal needle sticks to the genitals. “Ouch” is the first word that comes to mind.

What is a P shot? | The injectionMMA and P shot | P Shot Cost” $2,000 | Risks | The O shot | Big picture & overall reviewsReferences

P shot, Sean_O'Malley, P shot review
MMA fighter Sean O’Malley reportedly recently got a P shot intervention. Creative Commons licensed image.

What is a P shot?

Over the more than a dozen years of doing The Niche, I still get regular questions about this stuff. If anything, it seems that interest in this area has increased substantially over the years.  I believe people are losing money and there are real risks to these procedures.

What are these procedures?

A P shot is an injection of cellular material into the penis to supposedly enhance the organ. The “P” part of the name is for Priapus, an ancient god of fertility and gardens.

Google search metrics show that searches related to trying to get a bigger penis via cell therapy-related shots are very popular.

The claim by those who sell this stuff is that they’ll give safe and effective improvement of sexual experience via a larger penis using stem cells or related technologies. Contrary to that, my claim review as a stem cell biologist is that this is a risky procedure and it does not have proven benefits. The claims of more or better orgasms or increased libido don’t seem supported either.

Priapus Fresco
A fresco in Pompei of the fertility god Priapus for whom the P shot is named.

What is injected?

With a P shot the material is platelet rich plasma or PRP. It’s not actual stem cells. That often gets confused in media articles.

That’s probably because various doctors and clinics have sold supposed stem cell injections for male enhancement attempts as well. You can imagine that an injection into the penis will have risks, which I’ll discuss later in the post.

The one published study on the P-shot is largely inconclusive. At least no side effects were reported, I suppose. However, a small uncontrolled study isn’t convincing one way or another.

If you’re interested in this kind of thing, talk to your doctor who is not selling these shots. Note that I only searched for “P shot” by name in the title on PubMed. There are other articles in this space including one in JAMA Network that provides some data on who is giving these P shot type procedures, prices, and more. Some are not P shots but are related approaches.

Celebs and the P shot

At least once or twice a year some celebrity gets their penis injected with stem cells. Or related biological stuff. This brings so-called P-shots back to mind.

In the newest story, MMA fighter Sean O’Malley apparently described getting this done down in Mexico.

He seems to have rolled the dice that the injection will enhance his penis or sexual experience. I hope he’ll be okay.

Sometimes you see P shot before and after pictures, but how reliable are those? I don’t see any way to be sure.

Another celebrity earlier seems to have self-injected actual fat stem cells into his penis.

P shot risks

What are the P shot risks?

Many things could go wrong. The risks include infections.

There’s also a possibility of masses growing on the penis and lumps of injected material forming.

At another level, celebrities getting something in return for promotion of unproven procedures could change how they portray the results. In the past I’ve seen cases of celebs getting free “treatment” or even payments for promotion.

If you remember the full name of the injection here, note that the shot was named after the ancient god Priapus. Interestingly, an analysis of the fresco of this god at Pompei (see image above) by a doctor in modern times suggested the conclusion that rather than Priapus just being well-endowed, he may have had a medical problem with his penis.

If so, this ironically highlights the risks with P shots.

Shot costs: $2,000 and up

These procedures are also expensive.

A P shot costs about $2,000.

The costs could go higher depending on the clinic, the specific procedure, and repeat injections.

I believe it is a waste of money.

What is an O shot and associated risks?

An O shot is an experimental, unproven procedure to try to enhance female sexual experience.

The “O” stands for orgasm.

As with P shots, O shots are unproven and definitely have risks. I found no published papers on the O shot by name on PubMed.

I’ve written before about the issues with vaginal rejuvenation more generally. Here again, the injections contain PRP. Does it work?  I’m highly skeptical. There’s no reason to think an O shot will give someone more or better orgasms.

It is formally possible that a growth factor-rich solution like PRP in an O shot could do something, but I kind of doubt it.

Big picture & overall O shot and P shot reviews

Overall, is the P shot worth it? Is the O shot worth it? What about other very similar approaches to cell therapies for sexual enhancement or to try to treat dysfunction?

In each case, my overall claim check is that it’s very unlikely to be worth the risks and costs in either case.

Is the P shot permanent? The O shot? The answer is almost certainly “no.” The likely transient nature also means it’s going to be temporary and more expensive if you get more shots. Risks also increase with frequent injections.

All of these risks and limitations are currently unresolved.

References & notes

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