September 29, 2020

The Niche

Knoepfler lab stem cell blog

Search Results for: MUSE cells

4 min read

Are MUSE cells for real? Stem cells come in different types that vary in a key property called “potency”, but very few are pluripotent. The more potency, the greater the flexibility of a stem cell to make other cell types. Flexibility in the cellular world is power. The most powerful stem cells generally used are called “pluripotent”, which refers to a special kind of stem cell that can make all 200+ other types of cells in the body through differentiation. Pluripotent stem cells are hard …Read More

8 min read

Introduction to CAR-T cells CAR-T cells are an exciting cutting-edge technology that has been garnering great interest including in the stem cell field. Potential therapeutic uses of CAR-T, which stands for Chimeric Antigen Receptor T-Cells (CAR-T), are being studied in clinical trials as immunotherapies to potentially fight cancer as well as many other diseases by using one’s own immune system. The process of CAR-T therapy (see diagram below) starts off with the collection of the patient’s own T-cells through apheresis. The cells are then …Read More

4 min read

Something very strange just happened at the journal Nature related to what’s called Muse cells. Kudos to them for dealing with it quickly though. They published an unreviewed research “article” on controversial (perhaps non-existent) stem cells called “Muse cells” that was actually a paid advertisement. After I communicated with the Nature team eventually they ended up pulling down the ad/article as of today. How can a research article be an advertisement? I don’t think it should be possible. An “ad/article”? Of course, research journals run …Read More