June 1, 2020

The Niche

Knoepfler lab stem cell blog

Search Results for: MUSE cells

4 min read

Stem cells come in different types that vary in a key property called “potency”. The more potency, the greater the flexibility of a stem cell to make other cell types. Flexibility in the cellular world is power. The most powerful stem cells generally used are called “pluripotent”, which refers to a special kind of stem cell that can make all 200+ other types of cells in the body through differentiation. Pluripotent stem cells are hard to come by though. One of the more controversial areas …Read More

4 min read

Something very strange just happened at the journal Nature related to what’s called Muse cells. Kudos to them for dealing with it quickly though. They published an unreviewed research “article” on controversial (perhaps non-existent) stem cells called “Muse cells” that was actually a paid advertisement. After I communicated with the Nature team eventually they ended up pulling down the ad/article as of today. How can a research article be an advertisement? I don’t think it should be possible. An “ad/article”? Of course, research journals run …Read More

4 min read

Guest post by Lisa Willemse Last month, on this blog, Paul wrote an article about loopholes in the clinicaltrials.gov database that allows for-profit companies to advertise their “therapies” under the guise of a registered clinical trial. This is a real concern for our community, especially those among us who have recommended the clinicaltrials database as a source of information for patients who are considering an experimental treatment and wish to better understand the difference between a clinical trial and an unproven, cash-based therapy. Those …Read More

4 min read

If you take an ordinary cucumber and soak it in a mild acid solution of vinegar for a few weeks you get a pickle, which is where we find STAP stem cells. Recently, some scientists reported in Nature that if you take ordinary cells and soak them in a mild acid solution for 30 minutes, often the cells transformed into the most powerful type of stem cells known to science. These newly incarnated pluripotent or totipotent stem cells, which they termed “STAP” stem cells, reportedly …Read More

2 min read

Retraction Watch broke the news that Haruko Obokata of the STAP cell train wreck now has a 4th paper retraction. The publication related to the controversial idea that adult tissues have pluripotent potential or actual pluripotent stem cells in them so it was kind of foundational for the debunked STAP cell idea. It also reminds me of VSELs and MUSE cells too, which people to this day still publish about without much attention. There could be some retractions related to VSELs and MUSE cells …Read More