Search Results for: embryo models

When does a human embryo model become the real thing & other tough questions for a new field

human embryo model mukul tewary sm

A human embryo model is a laboratory-produced collection of living cells that has some key things in common with real human embryos. They are made from pluripotent stem cells, which include embryonic stem cells and induced pluripotent stem cells or iPS cells. This research is both exciting and ethically complicated, raising some difficult questions. Embryo …

When does a human embryo model become the real thing & other tough questions for a new field Read More »

Monkey human embryo chimera Cell paper: exciting, ethically complex direction

human embryo chimera

A new Cell paper from an international team led by Juan Carlos Izpisua Belmonte pushes human embryo chimera embryo research further than ever before. It is both exciting work and raises many complex bioethics questions at the same time. What is a human embryo chimera? By way of background, chimeric human embryos contain a mixture …

Monkey human embryo chimera Cell paper: exciting, ethically complex direction Read More »

Weekly reads: embryo pubs stir things up, organoids crying, & more

organoids tear glands sm

This was an unusual week in that three papers in a sense collided together related to embryo production and growth, raising new research possibilities but also serious ethical questions. New research: what is an embryo & what is not? The first two Nature papers reported generating the most realistic models of human embryos from scratch …

Weekly reads: embryo pubs stir things up, organoids crying, & more Read More »

New lab-grown blastoids are strikingly similar to human embryos

blastoids nature paper figure 2

A new word has been added to the lexicon of human stem cell research – blastoids, aka “blastocyst-like structures.” Unlike the familiar three-layered embryo that emerges during the third week of prenatal development, the earlier blastocyst resembles a fluid-filled soccer ball, with a smear of cells on the interior face destined to develop into the …

New lab-grown blastoids are strikingly similar to human embryos Read More »

Do human Very Small Embryonic-Like Stem Cells (VSEL) exist as a normal population of actual stem cells?

Supposedly there is a type of normal adult stem cell that intrinsically possesses many of the same properties as embryonic stem cells (ESCs). No reprogramming needed. No blastocysts needed. These reportedly amazing cells, called Very Small Embryonic-Like Stem Cells (VSELs), can in theory be isolated from umbilical cord blood (UCB) or even bone marrow. Yet …

Do human Very Small Embryonic-Like Stem Cells (VSEL) exist as a normal population of actual stem cells? Read More »

A look at “eyes on the brain organoids” Cell Stem Cell paper

brain organoids eyes

Sometimes a paper really catches your eye like a new Cell Stem Cell pub reporting eye-like structures grown on brain organoids. The paper is Human brain organoids assemble functionally integrated bilateral optic vesicles. Let’s take a quick look at this paper, its context, and the potential big-picture implications. Brain organoids with “eyes”? At first glance, …

A look at “eyes on the brain organoids” Cell Stem Cell paper Read More »

Weekly stem cell research reads: BAF, Polycomb, Fertility, More

jonathan hoggatt, Moderna, stem cell research

What might be most surprising about this week’s recommended stem cell research reads is there’s nothing about COVID-19 in here. There are, however, some really great papers. And we can expect more developments on the cellular medicine for COVID-19 front coming soon. Before I jump into the reads, if you haven’t already check out our …

Weekly stem cell research reads: BAF, Polycomb, Fertility, More Read More »

Hub of Regenerative Medicine & Stem Cell Meetings 2021

stem cell meetings 2021

Science must go on and so must stem cell meetings 2021 with all those great conferences out there, but this year it’s going to be different, right? Every year I put up a continually-updated list of stem cell meetings and conferences. I’ve got my 2021 even if most of what’s out there is going to …

Hub of Regenerative Medicine & Stem Cell Meetings 2021 Read More »

Recommended reads: a tale of human tails, heart reprogramming, pericytes, microglia

humans with tails

A piece on human tails and how we lost them caught my eye so I’ll start my weekly reads with that. This week I had the fewest Zoom meetings in ages, which allowed me to get more work done in my own lab and more reading. How about that? I even had some in-person meetings …

Recommended reads: a tale of human tails, heart reprogramming, pericytes, microglia Read More »

Human cloning is more likely now but would you take the big risks?

human cloning

I’ve been following the research related to human cloning now for more than a decade. Is human cloning more possible at this point? How do we even define such cloning? Did you know there are two types? The goal of this post is to educate you and in the process answer such questions. What’s in …

Human cloning is more likely now but would you take the big risks? Read More »