As we age a higher proportion of our cells end up in a senescent state, which has sparked interest in senolytic drugs and a broader area called senolytics research. The goal of today’s post is to give you an overview of this important area. How much data are there on efficacy or safety? Is the …
What are senolytics? Drugs, activator, supplements, risks Read More »
I took a look again into the world of stem cell supplements since it’s been a few years. What I found now in 2023 on stem cell pills wasn’t a pretty picture. This post has several sections so feel free to jump to specific sections below. I’ve also done a new YouTube video on stem …
Are long telomeres better than short ones? What about older folks lengthening their telomeres somewhat or stabilizing the length? Could this counter aging? As with many things, the story is far more complicated than we might hope. For background, telomeres are special structures protecting the ends of chromosomes. I remember as a young student that …
Long telomeres link to disease suggests caution on anti-aging push Read More »
Near-billionaire Bryan Johnson apparently does not like getting old and he’s trying to do something transformative about it. He and his team are experimenting in a big way. As a 55-year-old myself, I can’t blame him for wanting to fight aging in general. However, his anti-aging project includes some extreme stuff. Will some in the …
Skepticism on the Bryan Johnson anti-aging extravaganza Read More »
When people find out that I’m a stem cell researcher, a common question is whether there’s something they can take that is a stem cell activator. I’ve written before about whether there are stem cell boosts that one can do to try to be healthier. Sleep, stem cell activator and clonality Mostly when I bring …
Weekly reads: stem cell activator, sleep & stem cells, clonal hematopoiesis Read More »
Stem cell reviews of clinics and unproven therapies are an important relatively new part of The Niche. Data point to thousands of stem cell clinics in the U.S. selling a wide variety of supposed cell therapies. How does one evaluate such clinics? This question is on my mind regularly as so many patients ask me …
Stem cell reviews: clinics, therapies, & bad ideas Read More »
It seems like the field of cell biology has mixed feelings about fibroblasts so I’m going to start off there with the recommended reads. But first, check out our stem cell YouTube channel as we are steadily heading toward 500 subscribers and 30,000 views. Please subscribe. I’ve pasted one of our top videos below, which …
Weekly reads: fibroblasts, cancer stem cells, Parkinson’s Read More »
When we hear the word senile we might think stereotypically of an older person who has cognitive impairment, but some argue that senility can apply to cells too as they age and that such cells can be targeted by drugs called senolytics. Unfortunately, the supplements industry has picked up on this idea to sell iffy …
Recommended reads: senolytics, cow iPS cells, big CIRM royalty Read More »
Stem cell clinic firms often come and go rather quickly, but a few like Regenexx have persisted and even become a brand name. I’ve been writing here on The Niche for more than eleven years about stem cell clinics. Regenexx has been around that whole time. Along with its founder Dr. Chris Centeno. Patients have …
The news of the week relates to an interim clinical trial report from gene-editing firm Editas on its CRISPR trial for a form of vision loss. On to that in a minute. What have you been reading the past week? Below, I include our weekly list of recommended reads. However, first I wanted to give …
The Niche weekend reads: Editas mess, The Niche updates, papers Read More »