As we think about how much of a role belief should play in the hard sciences such as cell biology, a supposed cell type called VSEL or very-small embryonic stem cell-like cells comes to mind. For these guys it seems to me that the ratio of data to belief isn’t great. VSELs have nine lives. I […]
The role of belief in hard science: the VSEL case Read More »
A few people in the stem cell field keep arguing that adult pluripotent stem cells exist, including so-called “very small embryonic-like stem cells” or VSEL stem cells. These days the supposed cells are called VSELs or V-cells too. Only a handful of researchers have ever been able to report finding and studying these cells. Others
Fact-checking VSEL stem cells & VSEL treatment Read More »
It’s been quite a ride doing this blog on stem cells and other technologies for more than a dozen years. So far it seems like I’ll keep it going. A large part of the reason is because of people needing good information about our field. Those people include scientists and physicians but also many in
Weekly reads: Google, stem cells & MS, VSELs, ‘hairy’ organoids, MYC Read More »
The stem cell field has puzzled on and off for years over a constellation of papers on purported stem cells including so-called VSEL and MUSE cells. Many of us haven’t been convinced that these are real stem cells. I see VSEL and MUSE fitting into a larger pattern of dubious stem cell claims including the STAP
STAP cell deja vu? 28 VSEL papers flagged by Bik Read More »
Very small embryonic-like stem cells aka VSELs are reported to be tiny adult stem cells that are pluripotent or non-existent depending on whom you talk to most recently or which paper you just read. These very controversial cells (which I once compared to the Sasquatch) have a wildly fluctuating history with their existence on multiple occasions
Wild History of VSELs Predicts Future of STAP Cells? Read More »
One of the more controversial areas in the stem cell field has been over a stem cell type that only a handful of researchers have been able to find and study: very small embryonic-like stem cells or VSELs. These days some are calling them V-cells too. I’ve been getting an increasing number of questions from
What are VSELs and why are more clinics selling them? Read More »
I recently did a Q&A interview with NeoStem CEO Dr. Robin Smith. I posted Part 1 of that interview a few days ago here. Now we have part two focused on VSEL, ES cells, and iPS cells. PK: I frequently have readers of my blog ask questions about VSEL. They seem puzzled and unsure of
Interview with NeoStem CEO Robin Smith Part 2: VSEL, ES cells, and iPS cells Read More »
Supposedly there is a type of normal adult stem cell that intrinsically possesses many of the same properties as embryonic stem cells (ESCs). No reprogramming needed. No blastocysts needed. These reportedly amazing cells, called Very Small Embryonic-Like Stem Cells (VSELs), can in theory be isolated from umbilical cord blood (UCB) or even bone marrow. Yet
When I was first really getting into stem cells as a trainee the name Catherine Verfaillie came up as a scientist to watch in the adult stem cell area. It wasn’t too long after that though that I started hearing that some of the work from her lab at the University of Minnesota was being
Recommended reads: Nature Catherine Verfaillie retraction, Horvath paper, Vertex Read More »
The Mayo Clinic does some great research on stem cells and regenerative medicine. However, at times I’ve felt that a few Mayo researchers are overexuberant. This mainly relates to certain not-yet-proven stem cell and related offerings. Fitting with that perception, the Mayo website also has some inaccurate stem cell content that leans toward overstating things.
Key Mayo Clinic stem cell webpage is overexuberant & outdated Read More »