cancer stem cells Archives

Weekly reads: cancer stem cells, encouraging findings, Trump & NIH, proteomics

November 10, 2024 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Liver cancer stem cells, cancer stem cells

Cancer stem cells are stem cell-like cells in many tumors that are key contributors to the ability of tumors to persist and recur after treatment. For those reasons, they are also thought to be major targets, including of emerging therapies. Data also suggest that some therapies may create new types of cancer stem cells leading […]

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Weekly reads: cancer stem cells, Bik, & more

October 24, 2021 / Professor Paul Knoepfler, Ph.D. / 1 Comment

As many of you know I am a cancer survivor myself so studying cancer stem cells has meaning for me on another level. Cancer is also the possible side effect most patients worry about when considering going to an unproven stem cell clinic. I’ve got a new video up on possible stem cell side effects

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Weekly reads including MSCs & cancer stem cells

August 8, 2021 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

One of my main interests is the relationship between stem cells and cancer as well as what makes cancer stem cells tick. This week I’ve chosen to highlight articles on the role of stem cells in cancer plus other interesting publications. Cancer pubs related to stem cells including on cancer stem cells Identification of cancer-related

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Weekly reads: cancer stem cells & other pubs plus a puzzler

June 6, 2021 / Professor Paul Knoepfler, Ph.D. / 4 Comments

Cancer stem cells are one of the most interesting areas of research, intersecting the stem cell and cancer fields. Today’s weekly reads post highlights some new cancer stem cell articles along with some other interesting papers. I also note a recent weak stem cell clinical trial paper that is not a recommended read but is

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Weekly reads: court case, cancer stem cells, skin, pluripotency, & more

May 16, 2021 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

This was a busy week for me working on a grant due Friday and a bunch of other stuff including happily analyzing a bunch of data, but there were tons of interesting papers recently including on pluripotency. California stem cell clinic court case on in the background Along the way this week I was occasionally

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What is a teratoma tumor? Research & treatment

January 14, 2021 / Professor Paul Knoepfler, Ph.D. / 4 Comments

What is a teratoma? human stem cell teratoma knoepfler lab sm

Sometimes on The Niche or while teaching students as a professor here at UC Davis School of Medicine, I’ve been asked: What is a teratoma? Not all tumors are created equal and some like teratomas are particularly unusual. Exactly what is a teratoma tumor? Teratomas are germ cell tumors. What this means is that the

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Thought provoking talk from John Dick at ISSCR 2016 on cancer stem cells

June 23, 2016 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Dr. John Dick gave a great talk yesterday on cancer stem cells here at ISSCR 2016. Below I summarize his talk and as always with these meeting blogs, the post is not polished and is more of a stream of the speaker’s main points. He started out broadly with a nice introduction to this area of

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Can Stemcentrx thrive as a biotech killing cancer stem cells?

September 9, 2015 / Professor Paul Knoepfler, Ph.D.

A stem cell biotech in the news this week was one that had mostly flown under the radar previously with aim to zap cancer stem cells. Stemcentrx has a focus on killing cancer stem cells as a novel approach to treating cancer. Antonio Regalado had a nice article yesterday on the company. He reports that Stemcentrx has

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Cancer stem cells, shifting tides and an expanding understanding: guest post by Aaron Goldman

February 19, 2015 / Professor Paul Knoepfler, Ph.D. / 2 Comments

This is a guest post on Cancer stem cells By Aaron Goldman Much like the winter weather we’ve been enduring on the east coast, cancer research is advancing at a rapid clip! For decades, researchers have considered pools of “cancer stem cells” (CSC) as the subsets within a tumor which both initiate progression and underpin

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Are glioma stem cells a path to better outcomes?

June 25, 2014 / Professor Paul Knoepfler, Ph.D. / 3 Comments

Glioblastoma and other related malignant glioma tumors including diffuse intrinsic pontine glioma (DIPG) are some of the most devastating of all human cancers, and glioma stem cells may contribute to the lethality. You can see an image of a glioma (the white area in the brain scan) from Wikipedia above. These brain tumors usually kill

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