About once each year or two, I try to schedule what I call a “big picture” lab meeting where my lab and I discuss major issues related to being a scientist. Also, I try to answer their questions about just about anything. In my lab we rotate between various lab meeting formats and also have a journal club, but it’s worth taking up one slot for this big picture meeting where we just talk. At the big picture lab meeting, we some times end …Read More
What happens if we mix stem cells with populism? From a populist view of stem cells, everyday patients should be able to do nearly anything they want with stem cells without any governmental interference or excessive expense. Even stem cells not proven to be safe or effective. This can sound like an appealing idea to patients looking for hope and also to some companies looking for profits. Stem cell populism poses serious questions and risks too. What exactly is “populism”? The Internet defines it …Read More
There has been a wave of intense discussions both in the public domain such as on Twitter and behind the scenes over the new Egli, et al. preprint that challenges the main conclusions of the Ma, et al. Nature paper from Shoukhrat Mitalipov’s lab. Ma, et al. reported CRISPR gene editing of human embryos, arguing for a mechanism of HDR-based gene editing relying on interaction of the maternal and paternal genomes in the early embryos. Egli, et al. presented several alternative explanations — mostly involving …Read More
Reposted from my book, Stem Cells: An Insider’s Guide.
Here are some stem cell weekend reads for your enjoyment along with various links and headlines. Some science pubs that caught my eye: Human Neural Stem Cell Biodistribution and Predicted Tumor Coverage by a Diffusible Therapeutic in a Mouse Glioma Model High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain Identification for Differential Localization of Putative Corneal Epithelial Stem Cells in Mouse and Human Tracing the origins of relapse in acute myeloid leukaemia to …Read More
Hans Keirstead is one of the top stem cell scientists in the world who has been doing cutting edge research including on using stem cells to reverse paralysis where he teamed up with super patient advocate Roman Reed (see the two pictured at right), but now he is also running for Congress. How cool is that? Here is a quick Q&A interview with Hans today (see below). Please consider making a campaign contribution to support his candidacy. He would be amazing as a Congressman! When did …Read More