Search Results for: human germline

TGIF weekend reads: stem cells, GMOs, #CRISPR, cats, cloning and more

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Sounds recommended weekend reads for you to enjoy since it is Friday and almost the weekend including stem cells, CRISPR, cats, cloning, and more. Holy GMO, China wants to buy Syngenta. RetractionWatch says that Macchiarini will soon be out at Karolinska. For more on this “super surgeon” who used stem cells, see here regarding recent Vanity …

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Just freakin do it: patients voice impatience on CRISPR for genetic diseases

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Both before and particularly now after the big human gene editing summit in Washington, D.C. at the National Academy of Sciences, I’ve talked with patients about their views on this new technology including at last week’s World Stem Cell Summit. One of the most striking moments of the DC summit was when the mother of …

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Mitalipov Nature pub review: IPSC & SCNT for mitochondrial disease

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In a new, thought-provoking paper today in Nature, Shoukhrat Mitalipov and a multi-institutional team report a significant advance toward potential novel ways to treat mitochondrial diseases. What are these illnesses? Mitochondrial diseases are rare, but devastating disorders caused by genetic mutations. Today they are largely impossible to treat in meaningful ways other than palliative care. Some …

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A quartet of recent cool cell biology papers

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Cell biology research never ceases to surprise with its innovations. Here are four recent papers that strike me as interesting. YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate Self-Renewal and Vascular Mimicry of Stem-Like Cells. Stem Cells. Namrata Bora-Singhal, Jonathan Nguyen, Courtney Schaal, Deepak Perumal, Sandeep Singh, Domenico Coppola and Srikumar Chellappan. High burden and pervasive …

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CIRM Grantee Meeting on Wednesday March 6: fantastic talks by Drs. Storb & High

I’m here in San Francisco at the annual CIRM Grantee Meeting. As President Alan Trounson said, this is the best stem cell meeting in the world. We had two speakers tonight to kick off the meeting. Let me tell you my thoughts on each one. First, we had Rainer Storb from The Fred Hutchinson Cancer Research Center …

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Why miRNA iPS cells might be the ticket: an A+ paper

  Since Yamanaka’s discovery of iPS cells first in mouse and then in human cells 5 years ago, both made using viral transduction, a host of new methods to make iPS cells have been reported.  These methods are quite diverse, ranging from transposons, to recombinant proteins, to plasmids, and to RNA.  Often times these new …

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