I have a poll running regarding who would have been the best choice to share the Nobel Prize with Shinya Yamanaka and John Gurdon, and so far the winner is Ian Wilmut, who cloned the first mammal, Dolly the sheep. I should have included another option to indicate the possible preference that NO ONE should […]
Wilmut voted most-deserving of 3rd Nobel slot with Yamanka & Gurdon in poll Read More »
The stem cell community is buzzing today with excitement about the Nobel Prizes deservedly awarded to Shinya Yamanaka and John Gurdon for their pioneering work on cellular reprogramming. However, it is also just as worked up about the strange omission in this award of what could have been a third scientist awarded the prize for
Poll: who should have shared in stem cell Nobel Prize in third slot? Read More »
Are we ready to start using iPS cells in patients in the near future? Say in just a couple years? Are they ready for primetime? I think the answer is clearly “no”. I believe that iPS cells, a new type of stem cells, are one of the most exciting and important developments in biomedical sciences
iPS cells not quite ready for primetime? Read More »
What if I told you I believe that iPS cells really began in Seattle in the 1980s? Call me crazy? Read on. We hear a lot about how iPS cells were first created in 2006 in Japan by Shinya Yamanaka. I often say this myself. However, as is the case with so much in science,
How iPS cells germinated in part in Seattle in the 1980s Read More »
What are the most important iPS cell papers so far? 1) Yamanaka’s first paper on mouse iPS cells. Revolutionary. Intriguing perspectives presented in day 1 of the iPS cell field. Interesting statements such as Myc is required. Also take a look at those other reprogramming factors that he tested…there’s a tremendous amount there, largely unexamined.
What are the best iPS cell papers so far? Read More »
Do we still need iPS cells if transdifferentiation is so cool? Wait, how did we get to the point that people are asking me that extreme question? When iPS cells were first introduced to the world by Shinya Yamanaka, who I think will win the Nobel Prize sometime in the next few years, some folks went
Transdifferentiation does not make iPS cells obsolete Read More »
What is Myc? Often when we dig a little into the science of stem cells, people get turned off by all the strange names of molecules and jargon. However, whether you are a scientist, patient, investor, reporter, etc. there are some aspects of stem cell science that are ‘musts’ to know about. For example, you
Want to understand stem cells? Then you have to know Myc Read More »
George Bush deserves credit for iPS cells? No way. One of the weapons in the war against stem cell therapies is the use of a seemingly simple word: “ethical”. What does it mean to do ethical science in general and in particular what is ethical stem cell research? Who decides? According to the opponents of
News flash: George Bush deserves credit for iPS cells? Read More »
I have posted before about publishing trends in the iPS cell field here and in here…. but where do things stand today? Here, I provide an important update. What’s going on now? Here I provide answers to the key questions. How many papers are there on iPS cells? An interesting and unexpected trend for
Everything you need to know about publishing in the iPS cell field Read More »
Recently I polled my readers on how they make iPS cells and what the best method is in their opinion. The surprising results to date are above. The first thing that is striking is how dominant the Yamanaka method remains after 5 years. Despite scads of papers reporting new methods that are supposedly better in
Striking results from iPS cell poll Read More »