Every now and then I do a post on something fun and non-science related, and today it’s all about Seattle. Since it’s Friday, don’t you wish you were on vacation in Seattle? If you can ever imagine visiting Seattle in the near future, bookmark this page because I give suggestions for great things (some that …
Six fun, amazing, sometimes secret things to do in Seattle Read More »
Before stem cell research was on everyone’s minds and before the phrase “regenerative medicine” was familiar to most scientists, The Roman Reed Spinal Cord Injury Research Act of 1999 funded research into treating paralysis. It was a revolutionary piece of legislation, named after my friend Roman Reed, a true hero. Roman was playing college football …
Support Funding for the Roman Reed Spinal Cord Injury Research Program Read More »
A group of researchers led by Evan Snyder (paper discussed here) published a paper in PNAS on a new type of neural stem-like cell whose pluripotency can be turned ON or OFF by turning the v-myc gene ON or OFF using a conditional system of expression, called a “Tet-ON” system. In this system, tetracycline or its …
“Alternative” to IPS cells, ICSP, are very cool, but for now a no-go for the FDA Read More »
Great ideas are the foundation of science, but funding makes great ideas become realities and a monopoly on funding hurts science. UPDATE: NIH data backs up our conclusions: overfunding wastes precious resources–give the money to smaller labs. Arguably the key driver of the exciting progress in stem cell research is funding. With the stakes so …
Stem cell monopoly: do not pass go, do not collect $200,000 Read More »
It has been a rollercoaster few months between the anti-hESC court cases as well as Geron and Advanced Cell Technology (ACT) receiving the OK from the FDA to proceed with initial clinical trials of stem cell treatments. It’s OK to be excited about the clinical trials and I for one am, but we have to …
Challenges translating stem cell treatments to patients Read More »
Cancer is a class of diseases that are intimately linked to stem cells. In fact, I would go so far as to call some types of cancer cells and stem cells, cousins. This concept, of a tight relationship between stem and cancer cells, is under intense investigation but at the same time it is something …
This is the first post in a series focusing on stem cell advances related to specific diseases. Today we discuss Huntington’s Disease and a paper that came out yesterday in the journal Neuron that provides some significant insight into the mechanisms behind the disease. It is entitled: Huntingtin Is Required for Mitotic Spindle Orientation and …