CRISPR Cas9 is a relatively new, powerful approach to gene editing and genetic modification more generally. In the relatively short window of time in which this technology has been widely available for gene editing applications it has already evolved rapidly to become more powerful. Here are some new papers of interest on this technology. With […]
5 new cool papers on CRISPR Cas9 gene editing Read More »
It seems like Fridays are always a good time for reflection. It’s not like the scientist’s week ends on Friday sad to say, but still at least we can pause momentarily TGIF style and reflect on the maelstrom that is our lives, while cracking open another diet Coke or pouring another cup of coffee. This
TGIF: Stem Cell Stream of Consciousness Including CRISPR Read More »
CRISPR Cas9 gene editing technology is a game changer on many levels both inside and soon outside the lab. There is a growing sense of urgency amongst biomedical scientists to take a proactive approach to current and future use of CRISPR gene editing technology in human germ cells and embryos. These concerns have been heightened
Practical Plan for Managing Human Germline CRISPR Read More »
Why is CRISPR Cas9 gene editing such a big deal? Imagine being able to make mutations in any gene you wanted say in stem cells in a relatively simple, quick and affordable fashion? Sounds exciting, huh? Every so often a new kind of technology comes along in the biomedical sciences that is a true game
CRISPR Cas9 Gene Editing Tech Will Revolutionize Biology Read More »
Cancer stem cells are stem cell-like cells in many tumors that are key contributors to the ability of tumors to persist and recur after treatment. For those reasons, they are also thought to be major targets, including of emerging therapies. Data also suggest that some therapies may create new types of cancer stem cells leading
Weekly reads: cancer stem cells, encouraging findings, Trump & NIH, proteomics Read More »
For a few years, biophysicist He Jiankui might have been one of the most recognizable scientists on the planet. He made three “CRISPR babies” or gene edited people. However, his gene editing went badly and as best as we can tell his efforts did not result in precision edits. It’s unclear if he had institutional
What do patients who go to stem cell clinics really think of their experiences? It can be hard to get good data on this important question. For that reason, it was great to see a new article on this topic. With perhaps around 2,000 unproven clinics in the U.S., these firms are likely to have
People often ask me what is the most promising new cell therapy and while it is difficult to choose just one, I often highlight the promise of stem cells for diabetes. Here in the U.S., early data from diabetes clinical trials by Vertex look encouraging. Other teams worldwide are also working in this space and
It’s always fun to see startups with cool ideas in the regenerative medicine space and a new one called GC Therapeutics got some nice coverage this week. What do you think the name of this firm stands for? I have one main idea I mention below. Before we jump into it, I want to introduce
How are things going with regenerative medicine and stem cells in Japan? It’s still an exciting time there, but I’ve noted a sense that it is a time of transition too in some ways. For example, government funding is perhaps less certain than in the past. Let’s start with a few articles on how the
Recommended reads: Stem cells in Japan, iPS cells for COVID & hearts, He Jiankui Read More »