I wrote briefly a few months ago about Altos Labs. It’s a new kind of biotech institute that is focused on cellular reprogramming. Now we know much more and it’s clear this is a huge deal. What’s in this article What is Altos Labs? | Cellular rejuvenation | Reprogramming oldness | Challenges | Altos Strategies | Analysis of …
All about Altos Labs & its $3B cellular rejuvenation push Read More »
What’s on your weekend reads list including stem cell papers? In addition to hard-core research papers, I find some bigger picture publications to be helpful too. Then there are just fun items. Every so often I do a post about things that I’m hoping to find time to read over the weekend or that I’ve …
Recommended recent stem cell, cancer, & CRISPR reads Read More »
I received a score of great nominations for the Stem Cell Person of the Year 2016 Award and have briefly described the twenty nominees below. The point of the award is to honor the top positive stem cell leader who specifically thinks outside the box and takes risks. I’ve started an on-line vote where you can vote once per day for …
20 Nominees for Stem Cell Person of the Year 2016 Award Read More »
My to-read list this weekend includes a range of papers along with various news & media including a report of two US research groups aiming to get CRISPR baby patents. More on that below. At long last a trip + fun thing to do in NYC Last week I took my first trip in more …
Weekly reads: escape to New York, CRISPR baby patents, ISSCR guidelines, pubs Read More »
I managed to escape to do some hiking along the coast so I’m behind on my weekly reading and I’m just getting back here on The Niche. Here are some articles I’m hoping to catch up on in coming days including an interesting overview of stem cells for tooth repair. I sometimes have a wistful …
Weekly The Niche Reads: tooth repair, PRC2, beach pics Read More »
A new word has been added to the lexicon of human stem cell research – blastoids, aka “blastocyst-like structures.” Unlike the familiar three-layered embryo that emerges during the third week of prenatal development, the earlier blastocyst resembles a fluid-filled soccer ball, with a smear of cells on the interior face destined to develop into the …
New lab-grown blastoids are strikingly similar to human embryos Read More »
It’s fitting, given the edginess over the election, that Halloween is falling only a few days before election day so here is a list of recommended stem cell reads for you to dive into some biomedical science. Liver buds from stem cells Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and …
The stem cell universe is populated by sometimes mysterious acronyms (see an image of a whole alphabet stem cell acronym soup), many of which refer to specific kinds of stem cells including one nebulous type called MUSE cells. I’m not convinced that MUSE cells exist, but oddly there appear to be four clinical trials ongoing …
Dubious MUSE cells are in 4 Japanese stem cell trials Read More »
CRISPR and IPS cells are two of my favorite things so when they come together as in a cool, new paper from Sheng Ding’s lab, I’m excited to read it and curious as to what the scoop is. Since 2006-2007 when mouse and human reprogramming were first reported, many different methods have been explored to …
CRISPR to make IPS cells: review of new Ding lab paper Read More »
A new Cell paper from Juan Carlos Izpisua Berlmonte’s group has made headlines about anti-aging across the globe because it suggests that the four core induced pluripotent stem cell (IPSC) factors use by Shinya Yamanaka to make IPSC can reverse aging. I’ve pasted the graphical abstract from the paper below and done a quick journal club style …
Quick journal club on IPSC anti-aging paper: cool, but outstanding questions Read More »