Search Results for: chimeras

Surprising reason why human cloning may produce someone else

Daisuke-Takakura-human-cloning

“If I’m going to the trouble of cloning myself, I want the clone to be a copy of me!” I’m imagining what someone might say if they were told that their expensive and ethically dubious personal cloning efforts produced a clone that was somebody else instead of them. Even if the clone was very similar …

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Perspectives on pig human chimera paper

human-pig-chimera

A new paper focused on human and other chimeras just came out today in Cell reporting a number of findings, but most strikingly successful generation of human-pig chimeras in utero. The paper, entitled, “Interspecies Chimerism with Mammalian Pluripotent Stem Cells” describes various chimeras including mouse-rat ones, although those have previously been reported. This work comes …

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Grading my stem cell predictions for 2016: how’d I do?

stem-cell-predictions

Below are the 2016 stem cell predictions I made last year and their status now color-coded near year’s end. Green is right, orange is mixed bag, and red is flat out wrong. Overall, I did better than most past years with only having entirely blown it on four. Stay tuned later this week for my 2017 predictions, …

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Public stem cell skirmish erupts between Hanna & Jaenisch

Jaenisch-Hanna

Professor Rudolf Jaenisch of MIT and his former postdoc/now assistant professor at The Weizmann Jacob Hanna have gotten into a very public, stem cell skirmish over conflicting papers. Hanna raised concerns over a Jaenisch lab paper and things have escalated from there. This mess is playing out before our eyes on PubMed (there was a comment from Hanna …

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Stem cell checkup: how are my 2016 predictions doing half way?

Stem-Cell-Predictions

Each December I make stem cell predictions for the coming year and I did that for 2016 where I made 20 predictions. At around mid year I do a checkup on how my predictions are doing halfway and that is the purpose of this post. Below are my predictions that I made in 2015 for stem …

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In Depth Report from April 29th Paris Human Gene Edit Meeting

Paris-Gene-Editing-Meeting

Editor’s note. Caroline Simons attended both the April 28th (see her report on that here) and 29th Paris meetings on human gene editing/genetic modification. Today, we have her in depth report on the April 29th meeting. I have posted her piece in full with only minor edits. If you are in a rush you can …

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Recommended weekend reading on stem cells & science

human-animal-chimeras

I try to catch up on my science reading over the weekends and evenings. Here’s my recommended weekend reading on stem cells & science. Did I miss anything especially cool? Let me know in the comments. Direct reprogramming of skin cells into insulin-producing cells. I love direct reprogramming. Healios and Athersys Enter Into Regenerative Medicine Partnership. …

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Perspectives on Pedersen Lab Human-Mouse Chimera Paper

human-mouse-chimera

A new Cell Stem Cell paper by Victoria L. Mascetti and Roger Pedersen on human-mouse chimera modeling is quite interesting and important. I really enjoyed this short paper, but I do have a reservation about one way that it is being interpreted. The authors show that human pluripotent stem cells (hPSC) including induced pluripotent stem cells …

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