Search Results for: chimeras

Monkey-pig chimeras pub discouraging for similar human research toward organ transplants

pig-monkey-chimera-that-was-born-but-died

Michael Le Page over at The New Scientist reports on a new paper describing the birth of monkey-piglet chimeras. Unlike most such primate embryo chimeras formed in research in the past, these were allowed to be born. A litter of ten from the new monkey-pig research, two of which were chimeras, all rather quickly died […]

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Stem cell news bites: chimeras, Australian clinics, organoids & more

brain-organoids

Some recent developments in the stem cell world are worth a look. I’ve posted the headlines verbatim and the links to some of these stem cell news bites below. NIH Plans To Lift Ban On Research Funds For Part-Human, Part-Animal Embryos. NIH may allow funding of human-animal chimeras in certain cases. Stem cell ‘tourists’ flock to

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Weekend reads: sperm, stem cells, chimeras, STAP, DNA Apps

sperm-and-egg

Here are some cool science reads to enjoy this weekend. Lab-grown sperm made from stem cells can’t swim, but are able to fertilize eggs, reports Eric Boodman over at STAT. Mouse-human neural crest chimeras: Not only a matter of black and white. Clever title. Antonio Regalado writes about a DNA App Store coming soon to a

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Weekly reads: CRISPR sickle cell, Parkinson’s, pig-human chimera concerns

CRISPR gene editing

CRISPR gene editing has made rapid progress heading from bench to bedside. Perhaps the fastest has been its progress toward clinical use to combat sickle cell disease. We’ll start with a new paper on one major effort here. CRISPR gene editing. This process often involves cutting DNA, which then can be used as an opening to

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Vivek Ramaswamy & his surprising stem cell start

Vivek Ramaswamy

Many of us first became aware of Vivek Ramaswamy as a Republican candidate for President. He was most well-known prior to that as a biotech leader. Given that biotech background, I decided to learn more about him. Surprisingly, his biomedical efforts may have started with stem cells. That caught my attention. This was way back during

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Stem cells & the philosopher’s stone, P53, thyroid organoids

philosopher's stone

I hadn’t remembered the history of the philosopher’s stone until reading a new review article about stem cells and aging. Here’s the article. Is the philosopher’s stone to rejuvenate blood stem cells an epigenetic regulator? Nature Aging. This preview kind of piece discusses how inhibiting a specific factor called PHF6 can “rejuvenate” HSCs in mice.

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Weekly reads: chimera cat vs. chimeric rat, cheap sequencing, more

Venus, cat chimera

When you are a stem cell biologist and especially if you do a blog, you sometimes run across very strange things like a chimera cat. In this case, I stumbled on the whole topic of chimeric cats because I was searching for info on chimeric rats on Google. Of course, I was. It’s kind of

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Monkey human embryo chimera Cell paper: exciting, ethically complex direction

human embryo chimera

A new Cell paper from an international team led by Juan Carlos Izpisua Belmonte pushes human embryo chimera embryo research further than ever before. It is both exciting work and raises many complex bioethics questions at the same time. What is a human embryo chimera? By way of background, chimeric human embryos contain a mixture

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OCT4-SOX DNA dance, PRC2, a noisy competition & more cell weekly reads

EMBO-J-2020-Fig-3b-Salazar-Roa-et-al

What’s new in the stem cell, cell therapy, and regenerative medicine world as well as biomedical science more generally including cancer? There’s quite a bit of news as reflected in media pieces and new pubs. Today’s post is focused on pubs that just came out. For last week’s recommended reads see here. Oct4-Sox2 Nucleosome Binding

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Stem cell good news: novel cancer work, new CA bills, Alzheimer’s, & more pubs

stem-cells-alzheimers

There’s nothing like stem cell good news and interesting publications to perk one up on a Monday. Enjoy. What recent papers have struck you as exciting? Novel stem cell-based cancer approaches (Part 1) It was exciting when Fate Therapeutics got the first induced pluripotent stem cell (IPSC) IND in the U.S. for their IPSC-derived natural killer cell

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