Search Results for: embryonic stem cells

What are adult stem cells & their clinical applications?

mesenchymal cells

When someone uses the term “adult stem cells” you might think that simply means stem cells from adults. However, it’s not that simple. The goal of today’s post is to help you get all the key facts about adult stem cells. This includes the different types of adult stem cells and their clinical potential. What …

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Weekly reads: cancer stem cells & other pubs plus a puzzler

kyu yum nature cancer stem cells niche

Cancer stem cells are one of the most interesting areas of research, intersecting the stem cell and cancer fields. Today’s weekly reads post highlights some new cancer stem cell articles along with some other interesting papers. I also note a recent weak stem cell clinical trial paper that is not a recommended read but is …

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The Niche stem cell picture contest winners: gut & astrocytes

stem cell picture contest

I got some great entries for our The Niche stem cell picture contest. While I expected many bright colorful images, every year some of the pictures surprise me in certain ways. There was another surprise in that two entrants in the contest, both Assistant Professors, are sisters. A talented family! You can see the previous …

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Weekly reads & stem cell news: New York axes NYSTEM, fetal tissue rules reversed, pubs & more

stem cell book

It’s been a week with a wide variety of regenerative medicine papers and stem cell news. Here’s my earlier take from a few days ago on the Belmonte-led human-monkey chimeric embryo paper in Cell that broke this week. A few days ago I also put up a new video on our Stem Cell YouTube Channel …

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Multipotent & totipotent vs pluripotent stem cells

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

What’s the difference between multipotent stem cells, totipotent stem cells, and pluripotent stem cells? The goal of today’s post is to help you learn and be clear on the differences. What’s in this article Definition of stem cells |Totipotent vs pluripotent stem cells | Pluripotent stem cells | Multipotent stem cells | The best kind of stem …

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Recommended reads: stem cells on the brain, heart, COVID

ascl1 brain stem cells harris et al cell stem cell 2021 fig. 6

There are weeks when it seems like papers on stem cells keep popping up. It can be a challenge to keep up with reading all the papers you want to read. Other times it is cell biology news that keeps breaking. The big news of the past week or so was unfortunately the concerning development …

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Lawmaker indicted for selling fake stem cells for COVID & more

patricia derges indictment for fake stem cells sm

A grand jury indicted Missouri state representative and assistant physician Patricia Derges for allegedly selling and injecting patients with fake stem cells. The injection was reportedly just of amniotic fluid, but Derges allegedly claimed it was a stem cell treatment. NBC News was one of several media outlets that broke the story here after the …

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What are induced pluripotent stem cells or IPS cells & clinical prospects?

induced pluripotent stem cells clinical trials map

Induced pluripotent stem cells or IPS cells just might be the most exciting development in the stem cell field over the last 15 years. They have unique potential for clinical impact for regenerative medicine too, both through their use to produce differentiated cellular therapies and indirectly via disease modeling as well as drug screening. The …

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Spicy stem cell pathways & other recommended reads

Nociceptor-mediated HSC mobilization. "Schematic representation showing that nociceptive-nerve-derived CGRP, but not substance P, acts via CGRP receptors on HSCs to enhance their mobilization via a cAMP-mediated signalling pathway. "Gao et al Nature, Capsaicin acts via nociceptor signaling to mobilize blood stem cells.

The stem cell paper of the week is a fun one about how capsaicin and nociceptors reportedly mobilize blood stem cells.  However, since the authors only show this in mice, could it also happen in humans? They argue it’s likely happening in people too. Note that nociceptors are special structures in our bodies that sense …

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