Does aging do something to time so it seems like as you get older that time goes by faster? Remember as a little kid when summer seemed to last forever and car rides could be agonizingly long? I’ve heard two theories on this. One is that the brain’s baseline of activity slows down with aging […]
Weekly stem cell reads: aging & cells, iPS cell mutations, gut, more Read More »
Blastoids are lab-grown models of human embryos that represent a relatively new area of developmental biology research. The goal of today’s post is to give you everything you need to know about this topic. What’s in this article What are blastoids? | How are blastoids made? | Use in research | Blastoids challenges & Ethics
What are blastoids, roles in biomedical research, & ethical considerations Read More »
Great ideas and talented scientists are not enough as biomedical research needs funding and here in the U.S. that means having R01 grant success. The trends since 1995 are slowly heading the wrong way. The average age of getting your first R01 grant keeps getting older. There is also still a bit of a possible
Weekly reads: R01 grant trends, DPPA4, adult human neurogenesis debate Read More »
What are possible stem cell therapy side effects? This is a common question I get asked. Most often it is asked by patients who reach out. They usually refer to risks at unproven stem cell clinics Check out the YouTube video below on our stem cell channel including my video on stem cell therapy side
Stem cell therapy side effects & risks: infections, tumors & more Read More »
One of my favorite types of papers are those on stem cells and chromatin, and a new one in Current Biology caught my eye this week. My own lab website has the URL chromatin.com so that says something. You can also read more about our research here. Recommended reads: chromatin and stem cells, more Asymmetric
Weekly recommended reads including asymmetric division & chromatin Read More »
For more than a year in my first job as a scientist I isolated cells from umbilical cord veins and then tossed the tissue away, never realizing there was more there that could be useful in the form of something called Wharton’s jelly. What’s in this article Umbilical cord histology & Wharton’s jelly | What
What is Wharton’s jelly & its possible clinical uses? Read More »
Mere weeks into the COVID pandemic, stunning graphics began to appear depicting the path of devastation of SARS-CoV-2 through a human lung. It’s only recently that we’ve come to understand what, exactly, is happening on a cellular level. The new view is thanks to single-cell RNA-sequencing, which analyzes the abundance of messenger RNAs in individual
COVID Traps Alveoli Cells in a Curious Progenitor State, Squelching Lung Regeneration Read More »
A new word has been added to the lexicon of human stem cell research – blastoids, aka “blastocyst-like structures.” Unlike the familiar three-layered embryo that emerges during the third week of prenatal development, the earlier blastocyst resembles a fluid-filled soccer ball, with a smear of cells on the interior face destined to develop into the
New lab-grown blastoids are strikingly similar to human embryos Read More »
In the past many of us have wished there was a list of FDA-approved stem cell therapies. Patients and fellow scientists often asked me, but I couldn’t find a list. As a result, I made a comprehensive list, which is the focus of today’s post. I’ve updated the list now in 2024 with the great
List of FDA Approved Stem Cell Therapies & Drugs for 2024 Read More »
The title of a new article in Stem Cells and Development may seem audacious to those unfamiliar with the plight of the northern white rhino and the promise of induced pluripotent stem cells. But “Rewinding Extinction in the Northern White Rhinoceros” may turn out to be accurate for what a genetically diverse stem cell bank
Will Stem Cells Save the Northern White Rhino? Read More »