The National Academy of Sciences (NAS) summit on Human Gene Editing will begin in a few days on December 1 in Washington, D.C. This summit is in part the extension of discussions that started at a more informal meeting on CRISPR earlier this year in Napa organized by Jennifer Doudna and colleagues. The NAS meeting […]
Live Blogging NAS Human Gene Editing Summit: #GeneEditSummit Read More »
A draft agenda is now publicly available for the upcoming National Academy of Sciences (NAS) meeting on human gene editing. We now know a lot more about what to expect from this international gathering, which is called the International Summit on Human Gene Editing: A Global Discussion. The meeting will start on day 1 with
NAS Human Gene Editing Meeting: Agenda & Public Participation Read More »
Who will be speaking at the upcoming National Academy of Sciences (NAS) meeting on human gene editing? So far we haven’t known, but now we do (if you are eager to find out, skip to bottom of the post). The organizers of the meeting can be found here. Keep in mind that it is probable that
List of Speakers for NAS Meeting on Human Gene Editing Read More »
Many of us scientists, ethicists, and legal scholars are working on educational outreach to the public on the potential use of gene editing technologies like CRISPR to genetically modify human beings, but clearly there’s a long way to go and much more to do on this front. By the way, you may find this new
Public polling on human gene editing, moratorium Read More »
The Juan Carlos Izpisua Belmonte group published a Cell paper today on using gene editing to reverse mutations associated with human mitochondrial disease. The paper is Reddy, et al. and is entitled, “Selective Elimination of Mitochondrial Mutations in the Germline by Genome Editing”. The authors report success using TALEN-based gene editing or mitochondrial-direct restriction enzyme (mito-ApaLI)
Juan Carlos Izpisua Belmonte Cell Paper on Gene Editing for Mitochondrial Disease Read More »
I’m doing a series of interviews with leaders in the field on human germline modification with the first interview in this series with George Church and today’s second in this series is a conversation I had with Dr. Jennifer Doudna, a pioneer in CRISPR-Cas9 technology. Doudna is a Professor in MCB and Chemistry as well
Jennifer Doudna Interview on CRISPR, Human Gene Editing Read More »
CRISPR Cas9 is a relatively new, powerful approach to gene editing and genetic modification more generally. In the relatively short window of time in which this technology has been widely available for gene editing applications it has already evolved rapidly to become more powerful. Here are some new papers of interest on this technology. With
5 new cool papers on CRISPR Cas9 gene editing Read More »
The field recently saw Lanphier, et al. in Nature calling for a moratorium on human germilne CRISPR genetic modification. A number of additional stakeholders are expected to be weighing in soon on the issue of human germline gene editing. For example, a Science paper from others in the gene editing community is anticipated soon and may well have somewhat different perspectives. I’ve been
Intensifying dialogue on human germline gene editing Read More »
In a still ongoing on-line poll, readers of this blog show a pattern of consistently favoring a moratorium on genetic modification of human germ cells. With more than 150 votes cast, the top two answers are ‘strongly favor’ and ‘favor’ a moratorium on human germline genetic modification. Only 15% strongly opposed a moratorium. Overall those
Readers across the globe favor moratorium on gene editing of human germ cells in poll Read More »
Why is CRISPR Cas9 gene editing such a big deal? Imagine being able to make mutations in any gene you wanted say in stem cells in a relatively simple, quick and affordable fashion? Sounds exciting, huh? Every so often a new kind of technology comes along in the biomedical sciences that is a true game
CRISPR Cas9 Gene Editing Tech Will Revolutionize Biology Read More »