Search Results for: weekly reads

Stem cell weekly reads: Jamie Thomson, Lamin B1, CRISPR

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The big news of the week was a $3.6 million settlement by a stem cell clinic, StemGenex, and one of its doctors in a class-action suit. I covered this StemGenex settlement and so did Michael Hiltzik of the LA Times and Paul Schloesser at Endpoints. I’d say this was good news for the stem cell field …

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Stem cells for MS & other weekly reads: CRISPR, COVID & a bat cave, Huntington’s

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About 1 million people are living with multiple sclerosis in the U.S. alone with millions of other cases around the world so a huge effort has gone into trying to find new approaches to the disease including stem cells for MS. We’ll start our weekly recommended reads by talking about a new paper on MS …

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Weekly reads: possible rare HIV cure, stem cell chicken, FDA commish

HIV infected T cell, HIV cure

The idea of stem cells outright curing diseases is exciting and has powerful appeal, but media need to be careful about using the word cure in headlines and articles as we saw this week related to a possible HIV Cure. HIV cure via stem cells and chemo? The big news of the week was that …

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Weekly reads: MSC, p53, EuroGCT, fake fish, K27M CAR-T

mesenchymal cells

What exactly is a mesenchymal cell and what does the acronym MSC stand for these days? I took a stab recently at discussing mesenchymal cells and the MSC acronym so check that out. There is a great need for standards on MSCs and the products out there being marketed as MSCs are probably in reality …

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Weekly reads: CAR-T cell good news, Califf fight, stem cells on lymph

CAR-T-cell-infographic

Not everything in biomedical science is a ground-breaking discovery or clinical game-changer, but CAR-T cell technology is a combination of both. CAR-T cell good news We have such good news in this new pub on long-term benefits: Decade-long leukaemia remissions with persistence of CD4+ CAR T cells, Nature. Another recent CAR-T cell article, this one in Science, …

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Weekly reads: aging, CRISPR delivery, hair, oocytes, paralysis

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The big news of the week was the launch of Altos labs and their ambitious plan to tackle aging through cell therapies. Altos has recruited a large number of top cell biologists away from academia. That team plus top biotech execs and a $3B war chest make Altos one to watch in coming years. I …

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Weekly reads: hydra heads, iblastoids, new 8-year grants

Grant writers handbook, grants cartoon

What if you could get 8-year grants to do whatever biomedical research you wanted? This sounds like a dream for many of us in the life sciences, but the first news item this week is all about such a potential new funding approach. The item especially caught my eye as I’m going to be doing …

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Weekly reads: PRC2, 2 weird bits of news, pubs, COVID stem cell hype

PRC2 lineage commitment

I’d say the paper of the week is on how PRC2 mediated H3K27me3 can in some sense replace elements of DNA methylation to repress. Very cool. Here it is: Sex-specific chromatin remodelling safeguards transcription in germ cells, Nature. Weird stuff In a merger of opposites, City of Hope to buy Cancer Treatment Centers of America …

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Weekly reads: grad student life, cell barcoding, diabetes trial, more

ViaCyte capsule stem cells diabetes

Part of being a grad student is dealing with technologies related to your projects and their limitations. Sometimes I feel old when I remember the way we used to have to do things in the lab. As a grad student, I manually poured, ran, and read giant sequencing gels. Back then, gene synthesis of a …

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Weekly reads: R01 grant trends, DPPA4, adult human neurogenesis debate

NIH R01 grant trends

Great ideas and talented scientists are not enough as biomedical research needs funding and here in the U.S. that means having R01 grant success. The trends since 1995 are slowly heading the wrong way. The average age of getting your first R01 grant keeps getting older. There is also still a bit of a possible …

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