What are your weekend reads? Many of us scientists read up on specific articles over the weekend that caught our eye during the last week or two. Here are some of my weekend reads plus some other stuff that just generally looked really interesting or unusual. The list includes both primary papers and news articles […]
Stem cell & other science weekend reads: arteries, diabetes, iffy metaphors, & more Read More »
Here are some articles that look especially interesting on stem cells, cancer, and CRISPR. I was just at the SNO meeting in SFO on childhood brain tumors so those are on my mind more. Childhood cerebellar tumours mirror conserved fetal transcriptional programs (Nature) Childhood brain tumors “think” they are building organds in fetuses. H3.3 K27M depletion
Recommended recent stem cell, peds cancer & CRISPR reads Read More »
Stem cell news is always burbling up, sometimes right there in front of us on the web and other times via networks of people. Astellas news. Some may remember there used to be this pioneering stem cell biotech called ACT, which then became Ocata, and finally was acquired by the big company Astellas. One of
Stem cell news bites: Astellas trial, cystic fibrosis claim, a few cool papers Read More »
How cool is it that literally fuzzy new stem cells called “F-class cells” bring substantial new sharp focus to the cellular reprograming arena? Remember Project Grandiose led by the great stem cell scientist Andras Nagy? It’s a massive project intended to decipher what makes stem cells tick and how ordinary cells be changed or reprogrammed into powerful
Fuzzy New Stem Cells Bring Reprogramming into Focus Read More »
Two of my favorite things are stem cells and histones. When they both come together in one paper and it’s in my favorite journal, Cell Stem Cell, you’ve got my full attention. My own lab is especially interested in the roles of histones and Myc in stem cells. So when I saw a paper a paper from
Cool Cell Stem Cell Paper From Ishii Team on Histones & Reprogramming Read More »
What is “radically deterministic” cellular reprogramming? Jacob Hanna’s lab recently published a very high profile Nature paper on nearly 100% efficient iPS cell formation based on targeting a factor called Mbd3. This super efficiency is a major departure from past reported efficiencies. This morning here at the Till & McCulloch Stem Cell Meeting in Banff,
Jacob Hanna on Radically Deterministic Reprogramming @TMM2013 Read More »
It has been fascinating in the last year to see the unfolding story of mutations in histone variant H3.3 in pediatric glioblastoma and related tumors. It seems amazing that in just over a year, a whole new area of cancer research has rapidly progressed. As I discussed in a recent post, histone H3.3 is a
Allis lab Science paper on histone H3.3 in pediatric brain cancer Read More »