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Weekly stem cell reads: diabetic wound healing, clinic bad outcomes, pubs list

August 2, 2020 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

CLOCK-function-in-mesenchymal-stem-cells

What’s new this week in terms of reads includes a stem cell/drug combo for diabetic wonderments healing, more documentation of patient harms from stem cell clinics, and a list of recommending papers. Adult stem cells/glaucoma drug combo promotes diabetic wound healing in mice From a team of my UC Davis School of Medicine colleagues led […]

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OCT4-SOX DNA dance, PRC2, a noisy competition & more cell weekly reads

July 12, 2020 / Professor Paul Knoepfler, Ph.D. / 1 Comment

What’s new in the stem cell, cell therapy, and regenerative medicine world as well as biomedical science more generally including cancer? There’s quite a bit of news as reflected in media pieces and new pubs. Today’s post is focused on pubs that just came out. For last week’s recommended reads see here. Oct4-Sox2 Nucleosome Binding

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Stem cell news & pubs: Parkinson’s, Freezing, COVID, & More

May 31, 2020 / Professor Paul Knoepfler, Ph.D. / 7 Comments

Moll-et-al.-effect-of-freezing-on-stem-cells-stem-cell-news-FI

I find following both stem cell news and the stream of interesting publications to be kind of fun and thought-provoking. This past week or two has been very busy. Here is a news summary and list of notable pubs. Stem Cell News on Parkinson’s Disease There were a number of interesting developments on the Parkinson’s

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Deconstructing Rudy Giuliani ‘stem cells for COVID-19’ podcast & NK cell transplant idea

March 31, 2020 / Professor Paul Knoepfler, Ph.D. / 14 Comments

Robert-Hariri-talking-with-Rudy-Giuliani-on-testing-22stem-cells22-for-COVID19.

Rudy Giuliani has been tweeting all kinds of wild things about the novel coronavirus and is apparently very excited about the idea of “stem cells” for COVID-19 patients. What could go wrong, right? Giuliani starts vaguely tweeting about “stem cells” I wrote a few days ago about how Giuliani had been plugging an upcoming podcast

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Weekly recommended science reads: stem cells, CRISPR, cancer & more

March 1, 2020 / Professor Paul Knoepfler, Ph.D. / 1 Comment

CRISPR-for-muscular-dystrophy.-Zhang-et-al.-Science-2020.-Screenshot-of-Fig.-2-featured-image

There’s never enough time to get all of one’s science reading done, but we can try! It helps to have a list of “to-read” articles, whether actual research articles or media pieces. In the old days, I remember my mentors saying they literally had “piles” of journal articles on their coffee tables, bathrooms, bedrooms, etc.

MUSE cells are in 4 Japanese stem cell trials despite doubts

November 17, 2019 / Professor Paul Knoepfler, Ph.D. / 16 Comments

Professor-Mari-Dezawa-talking-about-MUSE-cells-on-national-TV-in-Japan.-Screenshot.

The stem cell universe is populated by sometimes mysterious acronyms (see an image of a whole alphabet stem cell acronym soup), many of which refer to specific kinds of stem cells including one nebulous type called MUSE cells. MUSE cells clinical trials I’m not convinced that MUSE cells exist, but oddly there appear to be

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Stem cell good news & pubs in late May 2019

May 26, 2019 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Sangeetha-Vadakke-Madathil-et-al.-screenshot-of-video-PNAS-2019

The exciting and sometimes downright crazy giant stem cell ecosystem of legit research and unproven stem cell clinics could use a dose of good news now and then. In today post, I highlight some upbeat news and some interesting recent pubs. Enjoy! From a team led by Hina Chaudhry, MD, Director of Cardiovascular Regenerative Medicine at

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Nature yanks article that was actually advertisement on controversial stem cells

February 22, 2019 / Professor Paul Knoepfler, Ph.D. / 4 Comments

Something very strange just happened at the journal Nature related to what’s called Muse cells. Kudos to them for dealing with it quickly though. They published an unreviewed research “article” on controversial (perhaps non-existent) stem cells called “Muse cells” that was actually a paid advertisement. After I communicated with the Nature team eventually they ended up

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TGIF weekend reads: senolytics, new CRISPR, stem cells, & 3 wacky things

July 13, 2018 / Professor Paul Knoepfler, Ph.D.

Over the weekends I try to catch up on more diverse reading and sometimes come up with a list of stuff I want to get to during this time, but I also put together weekend reads usually on Fridays as a kind of TGIF on The Niche for the wider audience here. So here’s the

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TGIF: Guns, stem cells, science weekends reads & good news

February 16, 2018 / Professor Paul Knoepfler, Ph.D.

Wakabayashi-et-al.-Cell-Stem-Cell-Figure-1F

I’ve got some TGIF recommend reads on stem cells, etc, but first, what a week, right? We need more action on preventing gun violence. It’s a uniquely American health crisis that doesn’t have to be. There’s no real, common sense reason that gun control can’t reduce mass killings of our kids and others like the

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