Search Results for: yamanaka

Why Yamanaka deserved the Nobel Prize for induced pluripotent stem cells

I believe and have argued for years that Shinya Yamanaka, the discoverer of induced pluripotent stem cells (aka iPS cells) deserves the Nobel Prize. I’m very glad today that he received it. Some readers may find it a bit ironic that I believe so strongly in this way since over the years I have often […]

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Nobel Prize 2012 for stem cells to Yamanaka & Gurdon: why only 2?

Nobel-Prize

Stem cell revolutionaries Drs. Shinya Yamanaka and John Gurdon have won the 2012 Nobel Prize for Physiology or Medicine. Gurdon cloned for the first animal, a frog, and Yamanaka produced induced pluripotent stem cells (iPSCs), a kind of stem cell with the power of pluripotency, but derived from ordinary non-stem cells. Gurdon’s work was based

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Weekly reads: Rusty Gage & stem cell awards, ASCL1, stem cells for a vulture

Rusty Gage

There should be more stem cell awards. Why not recognize more scientists and advocates? I used to do a Stem Cell Person of the Year Award. I have thought about bringing it back. What do you think? Scroll through some past posts on the Stem Cell Person of the Year Award. ISSCR gives out stem

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Recommended reads: Shinya interview, MYC-MAX & extra digits, microglia as a therapy, oocyte maintenance

N-myc, heterochromatin

The proto-oncogene MYC is one of those factors studied in thousands of papers. MYC and its dimerize partner MAX are also seemingly involved in just about everything. They have crucial roles in many kinds of stem cells including adult and embryonic stem cells. One way or another MYC induction seems very helpful for cellular reprogramming

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Weekly reads: embryonic stem cells, Parkinson’s, Alzheimer’s

Knoepfler lab stem cells

Early during my postdoc I was primarily interested in the role of Myc genes both in cancer and in stem cells, work that later included embryonic stem cells. These cells are often called ES cells. At first I first started studying N-Myc in neural stem cells using a conditional knockout approach. However, soon after I was

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Weekly reads: MD Stem Cells, embryo models & headaches, cell therapy trial updates

dr. jeffrey weiss, MD Stem Cells

There is still plenty of reason to worry about unproven stem cells being marketed in the U.S. and elsewhere around the world. I’ll start with a new item here in the U.S. on a firm called MD Stem Cells and end with a newly published paper about how things are going in Poland on this

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Perspectives on David Sinclair anti-aging Cell pub & in vivo reprogramming

methuselah mouse, anti-aging

About twenty years ago a science story made big news of a so-called anti-aging Methuselah gene. Methuselah gene and anti-aging The claim was that this DNA conferred long life on people. Hence the name Methuselah, which refers to a man from the Bible who reportedly lived 969 years. The so-called Methuselah gene was at first not a

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Weekly stem cell reads: bat stem cells, brainier organoids, more

bat stem cell

I’m working to send out a big grant on Tuesday so I’m busier than ever but a few stem cell and regenerative medicine stories caught my eye. I can’t write grants 24/7 without a few breaks although sometimes it feels like that’s what I’m doing. Bat stem cell derivation Pluripotent bat stem cells as a

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